Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | FOLH1 | Q04609 | 7/20 | 0.49 |
| ▸ | PLCD1 | P51178 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.45 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 3/20 | 0.45 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.45 |
| ▸ | PLG | P00747 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | PADI6 | Q6TGC4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16315933 | 0.97 | TDP1 (0.53) | TDP1FOLH1PLCD1PRSS1PRSS2 | |
| SCHEMBL13045423 | 0.94 | TDP1 (0.47) | TDP1FOLH1PLCD1PRSS1PRSS2 | |
| SCHEMBL13045429 | 0.93 | TDP1 (0.49) | TDP1FOLH1PLCD1PRSS1PRSS2 | |
| SCHEMBL16329968 | 0.92 | TDP1 (0.49) | TDP1FOLH1PLCD1PRSS1PRSS2 | |
| SCHEMBL16330041 | 0.91 | TDP1 (0.57) | TDP1FOLH1PLCD1PRSS1PRSS2 | |
| SCHEMBL12387460 | 0.90 | TDP1 (0.39) | TDP1FOLH1PLCD1PRSS1PRSS2 | |
| SCHEMBL14524594 | 0.89 | TDP1 (0.43) | TDP1FOLH1PLCD1PRSS1PRSS2 | |
| SCHEMBL16350682 | 0.88 | FOLH1 (0.51) | TDP1FOLH1PLCD1PRSS1PRSS2 | |
| SCHEMBL10085165 | 0.88 | PRSS1 (0.40) | TDP1FOLH1PLCD1PRSS1PRSS2 | |
| SCHEMBL16299318 | 0.86 | TDP1 (0.48) | TDP1FOLH1PLCD1PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110189692-A1 | ASSAY FOR PATHOGENIC CONFORMERS | NOVARTIS AG | 2011-08-04 | — | — | US | disclosed |