Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA5 | P31644 | 19/20 | 0.84 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.67 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL108791 | 0.92 | GABRA5 (0.82) | GABRA5 | |
| SCHEMBL2924430 | 0.91 | GABRA5 (1.00) | GABRA5 | |
| SCHEMBL2922234 | 0.91 | GABRA5 (1.00) | GABRA5GABRA1 | |
| SCHEMBL2923151 | 0.90 | GABRA5 (0.78) | GABRA5 | |
| SCHEMBL2924603 | 0.89 | GABRA5 (0.84) | GABRA5ITGA5GABRA1 | |
| SCHEMBL30592788 | 0.89 | GABRA1 (0.82) | GABRA5GABRA1 | |
| SCHEMBL30592827 | 0.89 | GABRA5 (0.77) | GABRA5GABRA1 | |
| SCHEMBL20241120 | 0.89 | GABRA5 (0.77) | GABRA5GABRA1 | |
| SCHEMBL20241113 | 0.89 | GABRA1 (0.82) | GABRA5GABRA1 | |
| SCHEMBL16333644 | 0.87 | GABRA5 (0.77) | GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2227467-B1 | ISOXAZOLO-PYRIDINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2014-12-31 | — | — | EP | disclosed |