Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPEP | Q07075 | 6/20 | 0.54 |
| ▸ | ANPEP | P15144 | 3/20 | 0.54 |
| ▸ | GABRP | O00591 | 2/20 | 0.52 |
| ▸ | GABRD | O14764 | 2/20 | 0.52 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.52 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.52 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.52 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.52 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.52 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.52 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.52 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.52 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.52 |
| ▸ | GABRE | P78334 | 2/20 | 0.52 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.52 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.52 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.52 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.52 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5195398 | 1.00 | ENPEP (0.54) | ENPEPANPEPGABRPGABRDGABRA1 | |
| SCHEMBL5195388 | 0.84 | ENPEP (0.47) | ENPEPANPEPGABRPGABRDGABRA1 | |
| SCHEMBL4541642 | 0.79 | ENPEP (0.50) | ENPEPANPEPGABRPGABRDGABRA1 | |
| SCHEMBL289090 | 0.78 | ENPEP (0.76) | ENPEPANPEPGABRPGABRDGABRA1 | |
| SCHEMBL30901210 | 0.78 | ENPEP (0.48) | ENPEPANPEPGABRPGABRDGABRA1 | |
| SCHEMBL289150 | 0.78 | ENPEP (0.48) | ENPEPANPEPGABRPGABRDGABRA1 | |
| SCHEMBL6512826 | 0.77 | — | — | |
| SCHEMBL28926335 | 0.77 | — | — | |
| SCHEMBL12031644 | 0.77 | — | — | |
| SCHEMBL3453632 | 0.76 | GABRP (0.48) | ENPEPANPEPGABRPGABRDGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2491022-B1 | DIAZEPAN DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTORS | HOFFMANN LA ROCHE (CH) | 2014-12-31 | — | — | EP | disclosed |