Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.55 |
| ▸ | HTR2A | P28223 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 7/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.43 |
| ▸ | SLC2A2 | P11168 | 2/20 | 0.43 |
| ▸ | SLC2A3 | P11169 | 2/20 | 0.43 |
| ▸ | DHFR | P00374 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16334307 | 0.83 | MAPT (0.68) | DRD2HTR2AALDH1A1RXFP1RAB9A | |
| SCHEMBL16334630 | 0.83 | MEN1 (0.57) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL23168043 | 0.82 | CNR2 (0.50) | ALDH1A1RXFP1RAB9AMEN1KMT2A | |
| SCHEMBL30152422 | 0.82 | CNR2 (0.50) | ALDH1A1RXFP1RAB9AMEN1KMT2A | |
| SCHEMBL16245768 | 0.82 | ALDH1A1 (0.51) | DRD2HTR2AALDH1A1RXFP1RAB9A | |
| SCHEMBL30852648 | 0.81 | KDM4E (0.49) | ALDH1A1RXFP1RAB9AMEN1KMT2A | |
| SCHEMBL30852546 | 0.81 | ALDH1A1 (0.51) | ALDH1A1RXFP1KMT2AHPGDKDM4E | |
| SCHEMBL14923786 | 0.81 | ALDH1A1 (0.51) | ALDH1A1RXFP1KMT2AHPGDKDM4E | |
| SCHEMBL22279004 | 0.81 | CNR2 (0.52) | ALDH1A1RXFP1RAB9AMEN1KMT2A | |
| SCHEMBL16334419 | 0.80 | AR (0.48) | ALDH1A1RXFP1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014207508-A1 | PYRIDYL COMPOUND SUITABLE FOR THE TREATMENT OF METABOLIC DISORDERS | Piramal Enterprises Limited (IN) | 2014-12-31 | — | — | WO | disclosed |