Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 13/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.66 |
| ▸ | GAA | P10253 | 2/20 | 0.66 |
| ▸ | DRD2 | P14416 | 1/20 | 0.58 |
| ▸ | HTR2A | P28223 | 1/20 | 0.58 |
| ▸ | DHFR | P00374 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | CLK1 | P49759 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | CASP1 | P29466 | 2/20 | 0.46 |
| ▸ | CASP7 | P55210 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16334287 | 0.83 | DRD2 (0.55) | MAPTALDH1A1HSD17B10GAADRD2 | |
| SCHEMBL30852648 | 0.79 | KDM4E (0.49) | ALDH1A1KMT2AMEN1HPGDRXFP1 | |
| SCHEMBL23168043 | 0.77 | CNR2 (0.50) | MAPTALDH1A1HSD17B10GAAKMT2A | |
| SCHEMBL30152422 | 0.77 | CNR2 (0.50) | MAPTALDH1A1HSD17B10GAAKMT2A | |
| SCHEMBL14923786 | 0.76 | ALDH1A1 (0.51) | ALDH1A1HSD17B10GAAKMT2AHPGD | |
| SCHEMBL30852546 | 0.76 | ALDH1A1 (0.51) | ALDH1A1HSD17B10GAAKMT2AHPGD | |
| SCHEMBL22279004 | 0.76 | CNR2 (0.52) | MAPTALDH1A1HSD17B10GAAKMT2A | |
| SCHEMBL8931652 | 0.74 | MAPT (0.69) | MAPTALDH1A1HSD17B10GAADRD2 | |
| SCHEMBL16245768 | 0.74 | ALDH1A1 (0.51) | MAPTALDH1A1GAADRD2HTR2A | |
| SCHEMBL16334970 | 0.74 | MAPT (0.50) | MAPTALDH1A1HSD17B10GAADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014207508-A1 | PYRIDYL COMPOUND SUITABLE FOR THE TREATMENT OF METABOLIC DISORDERS | Piramal Enterprises Limited (IN) | 2014-12-31 | — | — | WO | disclosed |