Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTR7 | P34969 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16334841 | 0.84 | ALDH1A1 (0.45) | ALDH1A1KMT2AMEN1KDM4EHPGD | |
| SCHEMBL16333978 | 0.82 | MAPT (0.50) | ALDH1A1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL16334614 | 0.80 | HTT (0.51) | ALDH1A1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL22495310 | 0.79 | GRIN2D (0.56) | ALDH1A1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL23580075 | 0.78 | ALDH1A1 (0.49) | ALDH1A1KMT2AMEN1HSD17B10KDM4E | |
| SCHEMBL25841222 | 0.78 | ALDH1A1 (0.44) | ALDH1A1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL22495493 | 0.77 | NPC1 (0.56) | ALDH1A1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL23625755 | 0.77 | ALDH1A1 (0.51) | ALDH1A1KMT2AMEN1KDM4ESMN1; SMN2 | |
| SCHEMBL21353591 | 0.76 | — | — | |
| SCHEMBL15800694 | 0.76 | PLD1 (0.73) | ALDH1A1KMT2AMEN1RAB9AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014207508-A1 | PYRIDYL COMPOUND SUITABLE FOR THE TREATMENT OF METABOLIC DISORDERS | Piramal Enterprises Limited (IN) | 2014-12-31 | — | — | WO | disclosed |