Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16334608 | 0.84 | ALDH1A1 (0.51) | ALDH1A1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL25841222 | 0.82 | ALDH1A1 (0.44) | ALDH1A1MAPTTP53SMN1; SMN2MEN1 | |
| SCHEMBL23580075 | 0.82 | ALDH1A1 (0.49) | ALDH1A1MAPTTP53SMN1; SMN2MEN1 | |
| SCHEMBL16245824 | 0.81 | ALDH1A1 (0.42) | ALDH1A1MAPTTP53SMN1; SMN2MEN1 | |
| SCHEMBL23625755 | 0.80 | ALDH1A1 (0.51) | ALDH1A1MAPTTP53SMN1; SMN2MEN1 | |
| SCHEMBL16333978 | 0.80 | MAPT (0.50) | ALDH1A1MAPTTP53SMN1; SMN2MEN1 | |
| SCHEMBL16245768 | 0.78 | ALDH1A1 (0.51) | ALDH1A1MAPTTP53SMN1; SMN2MEN1 | |
| SCHEMBL16245849 | 0.78 | SMN1; SMN2 (0.45) | MAPTTP53SMN1; SMN2GAA | |
| SCHEMBL3544476 | 0.78 | MAPT (0.54) | MAPTTP53SMN1; SMN2KMT2AKDM4E | |
| SCHEMBL16340023 | 0.76 | KMT2A (0.51) | ALDH1A1MAPTTP53SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014207508-A1 | PYRIDYL COMPOUND SUITABLE FOR THE TREATMENT OF METABOLIC DISORDERS | Piramal Enterprises Limited (IN) | 2014-12-31 | — | — | WO | disclosed |