Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | PLAU | P00749 | 1/20 | 0.45 |
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15073434 | 1.00 | SMN1; SMN2 (0.52) | SMN1; SMN2KDM4EPKML3MBTL1THRB | |
| SCHEMBL16336148 | 1.00 | SMN1; SMN2 (0.52) | SMN1; SMN2KDM4EPKML3MBTL1THRB | |
| SCHEMBL16336372 | 0.93 | SMN1; SMN2 (0.59) | SMN1; SMN2KDM4EPKML3MBTL1THRB | |
| SCHEMBL16336373 | 0.93 | SMN1; SMN2 (0.59) | SMN1; SMN2KDM4EPKML3MBTL1THRB | |
| SCHEMBL15073451 | 0.93 | SMN1; SMN2 (0.59) | SMN1; SMN2KDM4EPKML3MBTL1THRB | |
| SCHEMBL16336154 | 0.90 | SMN1; SMN2 (0.55) | SMN1; SMN2KDM4EPKML3MBTL1THRB | |
| SCHEMBL15073455 | 0.90 | SMN1; SMN2 (0.55) | SMN1; SMN2KDM4EPKML3MBTL1THRB | |
| SCHEMBL16336153 | 0.90 | SMN1; SMN2 (0.55) | SMN1; SMN2KDM4EPKML3MBTL1THRB | |
| SCHEMBL16382903 | 0.88 | SMN1; SMN2 (0.54) | SMN1; SMN2KDM4EPKML3MBTL1THRB | |
| SCHEMBL16382901 | 0.85 | L3MBTL1 (0.45) | SMN1; SMN2KDM4EL3MBTL1TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9334275-B2 | Processes for preparing indoles | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2016-05-10 | — | — | US | disclosed |
| US-20150005494-A1 | PROCESSES FOR PREPARING INDOLES | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2015-01-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150005494-A1 | PROCESSES FOR PREPARING INDOLES | IDO1, INMT, IDO2 | SMN1; SMN2 2546/4885KDM4E 2552/4885PKM 1849/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.