SCHEMBL1633641

SCHEMBL1633641

COc1ccc(CSCCN(Cc2ccc(Cl)nc2)CC(C)C)cc1

nearest known ligand 0.38

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
AOC3 Q16853 1/20 0.38
GAA P10253 1/20 0.38
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
TERT O14746 2/20 0.36
MMP2 P08253 3/20 0.35
MMP3 P08254 3/20 0.35
MMP9 P14780 3/20 0.35
MMP13 P45452 2/20 0.35
MAPT P10636 4/20 0.35
NPC1 O15118 1/20 0.34
ALDH1A1 P00352 1/20 0.34
RAB9A P51151 1/20 0.34
POLB P06746 1/20 0.34
LMNA P02545 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12723280 0.80 ALDH1A1 (0.35) GAAMAPTALDH1A1LMNA
SCHEMBL5593871 0.79 ALDH1A1 (0.33) MEN1KMT2AMAPTALDH1A1
SCHEMBL12723249 0.78 MEN1 (0.41) MEN1KMT2ATERTMAPTNPC1
SCHEMBL9319280 0.77 ALDH1A1 (0.41) GAAMAPTALDH1A1LMNA
SCHEMBL1632771 0.75 ALDH1A1 (0.42) MEN1KMT2AMAPTNPC1ALDH1A1
SCHEMBL1633688 0.75 BCHE (0.39) GAAMAPTALDH1A1LMNA
SCHEMBL1634269 0.75 ALDH1A1 (0.39) GAAMAPTNPC1ALDH1A1RAB9A
SCHEMBL1776316 0.74 ALDH1A1 (0.46) MEN1KMT2ATERTMAPTNPC1
SCHEMBL1632904 0.72 PLK1 (0.46) GAAMEN1KMT2ATERTMAPT
Ammonia Solution, Strong SCHEMBL3027164 0.71 GAA (0.56) AOC3GAAMMP2MMP3MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7932393-B2 Insecticidal (heteroarylalky)alkane thio and oxo amine derivatives FMC CORPORATION (US) 2011-04-26 US disclosed
US-20100261757-A1 Insecticidal (Heteroarylalky)alkane Thio and Oxo Amine Derivatives FMC CORPORATION 2010-10-14 US disclosed
WO-2007085356-A2 INSECTICIDAL (HETEROARYLALKYL)ALKANE THIO AND OXO AMINE DERIVATIVES BAYER CROPSCIENCE AG (DE) 2007-08-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100261757-A1 Insecticidal (Heteroarylalky)alkane Thio and Oxo Amine Derivatives DDT, AKR7A2, TAAR1 AOC3 246/4885GAA 3395/4885MEN1 4602/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.