Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1633688 | 0.88 | BCHE (0.39) | ALDH1A1L3MBTL1KDM4EGAAMAPT | |
| SCHEMBL1634269 | 0.88 | ALDH1A1 (0.39) | ALDH1A1L3MBTL1KDM4EGAAMAPT | |
| SCHEMBL12723280 | 0.85 | ALDH1A1 (0.35) | ALDH1A1L3MBTL1KDM4EGAAMAPT | |
| SCHEMBL1632771 | 0.80 | ALDH1A1 (0.42) | ALDH1A1L3MBTL1MAPTLMNASMN1; SMN2 | |
| SCHEMBL5048184 | 0.80 | HRH3 (0.50) | ALDH1A1L3MBTL1KDM4EGAAMAPT | |
| SCHEMBL5593871 | 0.79 | ALDH1A1 (0.33) | ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL9321540 | 0.79 | SMN1; SMN2 (0.45) | ALDH1A1L3MBTL1KDM4EGAAMAPT | |
| SCHEMBL14641819 | 0.77 | SMN1; SMN2 (0.44) | ALDH1A1L3MBTL1KDM4EGAAMAPT | |
| SCHEMBL1633641 | 0.77 | AOC3 (0.38) | ALDH1A1GAAMAPTLMNA | |
| SCHEMBL14600317 | 0.77 | ALDH1A1 (0.45) | ALDH1A1L3MBTL1KDM4EGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5334724-A | Preparation of substituted 2-chloropyridines | BAYER AKTIENGESELLSCHAFT (DE) | 1994-08-02 | — | — | US | disclosed |
| EP-0438691-B1 | Process for the preparation of substituted 2-chloropyridines | BAYER AG (DE) | 1994-02-16 | — | — | EP | disclosed |
| EP-0370317-B1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED 2-CHLOROPYRIDINES | BAYER AG (DE) | 1993-06-02 | — | — | EP | disclosed |
| EP-0438691-A1 | Process for the preparation of substituted 2-chloropyridines | BAYER AG (DE) | 1991-07-31 | — | — | EP | disclosed |
| US-5010201-A | Process for the preparation of substituted 2-chloropyridines | BAYER AKTIENGESELLSCHAFT (DE) | 1991-04-23 | — | — | US | disclosed |
| EP-0370317-A1 | Process for the preparation of substituted 2-chloropyridines | BAYER AG (DE) | 1990-05-30 | — | — | EP | disclosed |