Known targets — ChEMBL curated mechanism
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The experimentally established mechanism targets of Sulfosalicylic. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.83 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.83 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.83 |
| ▸ | HPGD | P15428 | 3/20 | 0.83 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | CA7 | P43166 | 2/20 | 0.52 |
| ▸ | CA9 | Q16790 | 2/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.52 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.52 |
| ▸ | CA4 | P22748 | 1/20 | 0.52 |
| ▸ | CA6 | P23280 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.52 |
| ▸ | HNF4A | P41235 | 4/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfosalicylic SCHEMBL8994215 | 0.93 | ALDH1A1 (0.83) | ALDH1A1KDM4EHSD17B10HPGDMEN1 | |
| Sulfosalicylic SCHEMBL6717073 | 0.93 | ALDH1A1 (0.96) | ALDH1A1KDM4EHSD17B10HPGDMEN1 | |
| Sulfosalicylic SCHEMBL34766 | 0.93 | ALDH1A1 (0.96) | ALDH1A1KDM4EHSD17B10HPGDMEN1 | |
| Sulfosalicylic SCHEMBL29364125 | 0.93 | ALDH1A1 (0.96) | ALDH1A1KDM4EHSD17B10HPGDMEN1 | |
| Sulfosalicylic SCHEMBL25356542 | 0.91 | ALDH1A1 (0.93) | ALDH1A1KDM4EHSD17B10HPGDMEN1 | |
| Sulfosalicylic SCHEMBL3297465 | 0.91 | ALDH1A1 (0.93) | ALDH1A1KDM4EHSD17B10HPGDMEN1 | |
| Sulfosalicylic SCHEMBL818713 | 0.91 | ALDH1A1 (1.00) | ALDH1A1KDM4EHSD17B10HPGDMEN1 | |
| Sulfosalicylic SCHEMBL6536793 | 0.91 | ALDH1A1 (0.93) | ALDH1A1KDM4EHSD17B10HPGDMEN1 | |
| Sulfosalicylic SCHEMBL16908545 | 0.91 | ALDH1A1 (0.93) | ALDH1A1KDM4EHSD17B10HPGDMEN1 | |
| Sulfosalicylic SCHEMBL11042779 | 0.91 | ALDH1A1 (0.93) | ALDH1A1KDM4EHSD17B10HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150004711-A1 | METHODS AND ASSAYS RELATING TO PROSTATE CANCER | THE GENERAL HOSPITAL CORPORATION (US) | 2015-01-01 | — | — | US | disclosed |