Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9805456 | 0.98 | TSHR (0.62) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL9805477 | 0.98 | TSHR (0.62) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL692094 | 0.94 | TSHR (0.56) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL6037331 | 0.86 | THRB (0.52) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL29078693 | 0.84 | TSHR (0.54) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL5144090 | 0.84 | TSHR (0.79) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL25426 | 0.84 | TSHR (0.79) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL1455777 | 0.83 | TSHR (0.61) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL3620054 | 0.83 | TSHR (0.61) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL22554413 | 0.82 | TSHR (0.83) | TSHRPOLBAPEX1HTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 203 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240409563-A1 | HIGH PURITY POLYSILOXANE MACROMERS AND METHOD FOR MAKING THE SAME | GELEST, INC. | 2024-12-12 | — | — | US | claimed |
| US-20230183273-A1 | HIGH PURITY POLYSILOXANE MACROMERS AND METHOD FOR MAKING THE SAME | GELEST, INC. | 2023-06-15 | — | — | US | claimed |
| US-11597789-B2 | Materials for hydrophilic interaction chromatography and processes for preparation and use thereof for analysis of glycoproteins and glycopeptides | WATERS TECHNOLOGIES CORPORATION (US) | 2023-03-07 | — | — | US | claimed |
| CN-113956727-B | Colorant composition and coated article | 广东华润涂料有限公司 | 2023-02-17 | — | — | CN | claimed |
| CN-113956727-A | Colorant composition and coated article | 广东华润涂料有限公司 | 2022-01-21 | — | — | CN | claimed |
| US-11092574-B2 | Materials for hydrophilic interaction chromatography and processes for preparation and use thereof for analysis of glycoproteins and glycopeptides | WATERS TECHNOLOGIES CORPORATION (US) | 2021-08-17 | — | — | US | claimed |
| US-20190056360-A1 | MATERIALS FOR HYDROPHILIC INTERACTION CHROMATOGRAPHY AND PROCESSES FOR PREPARATION AND USE THEREOF FOR ANALYSIS OF GLYCOPROTEINS AND GLYCOPEPTIDES | WATERS TECHNOLOGIES CORPORATION | 2019-02-21 | — | — | US | claimed |
| US-10119944-B2 | Materials for hydrophilic interaction chromatography and processes for preparation and use thereof for analysis of glycoproteins and glycopeptides | WATERS TECHNOLOGIES CORPORATION (US) | 2018-11-06 | — | — | US | claimed |
| US-20150204824-A1 | MATERIALS FOR HYDROPHILIC INTERACTION CHROMATOGRAPHY AND PROCESSES FOR PREPARATION AND USE THEREOF FOR ANALYSIS OF GLYCOPROTEINS AND GLYCOPEPTIDES | WATERS TECHNOLOGIES CORPORATION | 2015-07-23 | — | — | US | claimed |
| US-20110244203-A1 | SILANE ACRYLATE CONTAINING INTERMEDIATE TRANSFER MEMBERS | XEROX CORPORATION (US) | 2011-10-06 | — | — | US | claimed |
| WO-2003040700-A1 | HYDROPHOBIC SURFACE CHIP | CIPHERGEN BIOSYSTEMS, INC. (US) | 2003-05-15 | — | — | WO | claimed |
| US-20030032043-A1 | Latex based adsorbent chip | CIPHERGEN BIOSYSTEMS, INC. | 2003-02-13 | — | — | US | claimed |
| US-20030017464-A1 | Latex based adsorbent chip | CIPHERGEN BIOSYSTEMS, INC. | 2003-01-23 | — | — | US | claimed |
| US-6046293-A | Solid-liquid phase interfacial polymerization | UNIVERSITY OF SOUTH AUSTRALIA (AU) | 2000-04-04 | — | — | US | claimed |
| US-5811565-A | TREATING MIXTURE WITH LEWIS ACID HALIDE | DOW CORNING TORAY SILICONE CO., LTD. (JP) | 1998-09-22 | — | — | US | claimed |
| EP-0799851-A2 | Preparation of polyorganosilloxanes by interfacial polymerization | DOW CORNING CORPORATION (US) | 1997-10-08 | — | — | EP | claimed |
| US-5629401-A | Preparation of polyorganosiloxanes by interfacial polymerization | DOW CORNING CORPORATION (US) | 1997-05-13 | — | — | US | claimed |
| EP-0593297-B1 | Resin composition for coating and paint | HITACHI CHEMICAL CO LTD (JP) | 1997-04-16 | — | — | EP | claimed |
| US-5039761-A | Addition-condensation copolymers; waterproofing, sliding, gas permeability | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1991-08-13 | — | — | US | claimed |
| EP-0311348-A2 | Novel macromers containing a polyether moiety, process of preparing them and polymers thereof | Nippon Oil Co., Ltd. (JP) | 1989-04-12 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240409563-A1 | HIGH PURITY POLYSILOXANE MACROMERS AND METHOD FOR MAKING THE SAME | SSRP1, RPLP2, RPLP1 | TSHR 1897/4885POLB 307/4885APEX1 404/4885 |
| US-20230183273-A1 | HIGH PURITY POLYSILOXANE MACROMERS AND METHOD FOR MAKING THE SAME | SSRP1, RPLP2, RPLP1 | TSHR 1897/4885POLB 307/4885APEX1 404/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.