SCHEMBL692094

SCHEMBL692094

C=C(C)C(=O)OCCC[SiH](Cl)Cl

nearest known ligand 0.56

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.56
THRB P10828 1/20 0.48
POLB P06746 1/20 0.46
APEX1 P27695 1/20 0.46
HTT P42858 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
ALDH1A1 P00352 3/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1633952 0.94 TSHR (0.59) TSHRTHRBPOLBAPEX1HTT
SCHEMBL9805477 0.93 TSHR (0.62) TSHRTHRBPOLBAPEX1HTT
SCHEMBL9805456 0.93 TSHR (0.62) TSHRTHRBPOLBAPEX1HTT
SCHEMBL6037331 0.88 THRB (0.52) TSHRTHRBPOLBAPEX1HTT
SCHEMBL9847146 0.87 TSHR (0.55) TSHRTHRBPOLBAPEX1HTT
SCHEMBL2468776 0.84 TSHR (0.60) TSHRTHRBPOLBAPEX1HTT
SCHEMBL2307199 0.82 TSHR (0.58) TSHRTHRBPOLBAPEX1HTT
SCHEMBL19399230 0.82 TSHR (0.58) TSHRTHRBPOLBAPEX1HTT
SCHEMBL25426 0.81 TSHR (0.79) TSHRTHRBPOLBAPEX1HTT
SCHEMBL182045 0.81 TSHR (0.72) TSHRTHRBPOLBAPEX1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 145 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180277787-A1 THERMALLY STABLE SILVER NANOWIRE TRANSPARENT ELECTRODE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2018-09-27 US claimed
US-9823520-B2 Liquid crystal display apparatus and method for manufacturing the same SAMSUNG DISPLAY CO., LTD. (KR) 2017-11-21 US claimed
US-20150168763-A1 LIQUID CRYSTAL DISPLAY APPARATUS AND METHOD FOR MANUFACTURING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2015-06-18 US claimed
US-8614278-B2 Silicone acrylate hybrid composition and method of making same DOW CORNING CORPORATION (US) 2013-12-24 US claimed
EP-2599847-A1 A Silicone Acrylate Hybrid Composition and Method of Making Same Dow Corning Corporation (US) 2013-06-05 EP claimed
CN-103130966-A A silicone acrylate hybrid composition and method of making same DOW CORNING 2013-06-05 CN claimed
EP-2024406-B1 A SILICONE ACRYLATE HYBRID COMPOSITION DOW CORNING (US) 2012-08-01 EP claimed
US-20120114737-A1 SILICONE ACRYLATE HYBRID COMPOSITION AND METHOD OF MAKING SAME DOW SILICONES CORPORATION 2012-05-10 US claimed
CN-101501088-B Silicone acrylate hybrid compositions DOW CORNING CORP. (US) 2011-11-30 CN claimed
US-20090196911-A1 Silicone Acrylate Hybride Composition and Method Of Making Same DOW SILICONES CORPORATION 2009-08-06 US claimed
CN-101501088-A Silicone acrylate hybrid compositions DOW CORNING (US) 2009-08-05 CN claimed
EP-2024406-A2 A SILICONE ACRYLATE HYBRID COMPOSITION DOW CORNING CORPORATION (US) 2009-02-18 EP claimed
EP-1940368-A2 TRANSDERMAL DRUG DELIVERY SYSTEM WITH ACRYLATE OR METHACRYLATE FUNCTIONAL PRESSURE SENSITIVE ADHESIVE COMPOSITION DOW CORNING CORPORATION (US) 2008-07-09 EP claimed
WO-2007145996-A9 A SILICONE ACRYLATE HYBRID COMPOSITION DOW CORNING (US) 2008-02-14 WO claimed
WO-2007145996-A2 A SILICONE ACRYLATE HYBRID COMPOSITION DOW CORNING CORPORATION (US) 2007-12-21 WO claimed
WO-2007050580-A2 TRANSDERMAL DRUG DELIVERY SYSTEM WITH ACRYLATE OR METHACRYLATE FUNCTIONAL PRESSURE SENSITIVE ADHESIVE COMPOSITION DOW CORNING CORPORATION (US) 2007-05-03 WO claimed
EP-0311348-A2 Novel macromers containing a polyether moiety, process of preparing them and polymers thereof Nippon Oil Co., Ltd. (JP) 1989-04-12 EP claimed
EP-4395749-B1 TRANSDERMAL THERAPEUTIC SYSTEM FOR THE TRANSDERMAL ADMINISTRATION OF GUANFACINE COMPRISING GUANFACINE AND A MONO-CARBOXYLIC ACID LTS LOHMANN THERAPIE SYSTEME AG (DE) 2025-11-19 EP disclosed
US-5051486-A Comb like polymers containing siloxane groups with polyoxyalkylene groups NIPPON OIL CO., LTD. (JP) 1991-09-24 US disclosed
EP-0311348-A2 Novel macromers containing a polyether moiety, process of preparing them and polymers thereof Nippon Oil Co., Ltd. (JP) 1989-04-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120114737-A1 SILICONE ACRYLATE HYBRID COMPOSITION AND METHOD OF MAKING SAME MMS19, CAD, ACR TSHR 4740/4885THRB 4095/4885POLB 3051/4885
US-20090196911-A1 Silicone Acrylate Hybride Composition and Method Of Making Same MMS19, CAD, ACR TSHR 4760/4885THRB 4098/4885POLB 3022/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.