Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 3/20 | 1.00 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.73 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.68 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.68 |
| ▸ | XPO1 | O14980 | 1/20 | 0.68 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.68 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.68 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | CA7 | P43166 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30379956 | 0.90 | PDE4D (0.81) | PDE4DABCB1CYP3A4ALDH1A1PTGS2 | |
| Osthole SCHEMBL29595542 | 0.81 | PTGS2 (1.00) | PDE4DABCB1CYP3A4ALDH1A1PTGS2 | |
| Osthole SCHEMBL50436 | 0.81 | PTGS2 (1.00) | PDE4DABCB1CYP3A4ALDH1A1PTGS2 | |
| Osthole SCHEMBL17513161 | 0.81 | PTGS2 (1.00) | PDE4DABCB1CYP3A4ALDH1A1PTGS2 | |
| SCHEMBL15941538 | 0.81 | PDE4D (1.00) | PDE4DABCB1CYP3A4ALDH1A1PTGS2 | |
| SCHEMBL13532216 | 0.81 | PDE4D (0.67) | PDE4DABCB1CYP3A4ALDH1A1PTGS2 | |
| SCHEMBL3179673 | 0.81 | PDE4D (0.67) | PDE4DABCB1CYP3A4ALDH1A1PTGS2 | |
| Osthole SCHEMBL27681201 | 0.80 | PTGS2 (0.97) | PDE4DABCB1CYP3A4ALDH1A1PTGS2 | |
| Osthole SCHEMBL27950752 | 0.80 | PTGS2 (0.97) | PDE4DABCB1CYP3A4ALDH1A1PTGS2 | |
| Osthole SCHEMBL27803504 | 0.78 | PTGS2 (0.92) | PDE4DABCB1CYP3A4ALDH1A1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140377386-A1 | PLANT-BASED INHIBITORS OF KETOHEXOKINASE FOR THE SUPPORT OF WEIGHT MANAGEMENT | ACCESS BUSINESS GROUP INTERNATIONAL LLC (US) | 2014-12-25 | — | — | US | claimed |
| CN-122038214-A | Bacillus helman and application thereof | 湖北夏及复合益生物科技有限公司 | 2026-05-15 | — | — | CN | disclosed |
| US-20250177348-A1 | Methods for Fructokinase Meditation of Alcohol Craving and Alcohol Induced Liver Disease | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE | 2025-06-05 | — | — | US | disclosed |
| US-12161621-B2 | Methods for fructokinase mediation of alcohol craving and alcohol induced liver disease | THE REGENTS OF THE UNIVERSITY OF COLORADO | 2024-12-10 | — | — | US | disclosed |
| US-20210275494-A1 | METHODS FOR FRUCTOKINASE MEDIATION OF ALCOHOL CRAVING AND ALCOHOL INDUCED LIVER DISEASE | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE | 2021-09-09 | — | — | US | disclosed |
| WO-2020046481-A2 | METHODS FOR FRUCTOKINASE MEDIATION OF ALCOHOL CRAVING AND ALCOHOL INDUCED LIVER DISEASE | REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) | 2020-03-05 | — | — | WO | disclosed |
| EP-3010520-A1 | PLANT-BASED INHIBITORS OF KETOHEXOKINASE FOR THE SUPPORT OF WEIGHT MANAGEMENT | Access Business Group International LLC (US) | 2016-04-27 | — | — | EP | disclosed |
| US-20140377386-A1 | PLANT-BASED INHIBITORS OF KETOHEXOKINASE FOR THE SUPPORT OF WEIGHT MANAGEMENT | ACCESS BUSINESS GROUP INTERNATIONAL LLC (US) | 2014-12-25 | — | — | US | disclosed |
| WO-2014204853-A1 | PLANT-BASED INHIBITORS OF KETOHEXOKINASE FOR THE SUPPORT OF WEIGHT MANAGEMENT | ACCESS BUSINESS GROUP INTERNATIONAL LLC (US) | 2014-12-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12161621-B2 | Methods for fructokinase mediation of alcohol craving and alcohol induced liver disease | KHK, GCK, FN3K | PDE4D 2516/4885ABCB1 4238/4885CYP3A4 1116/4885 |
| US-20140377386-A1 | PLANT-BASED INHIBITORS OF KETOHEXOKINASE FOR THE SUPPORT OF WEIGHT MANAGEMENT | KHK, GCK, HK1 | PDE4D 3523/4885ABCB1 2218/4885CYP3A4 1346/4885 |
| US-20210275494-A1 | METHODS FOR FRUCTOKINASE MEDIATION OF ALCOHOL CRAVING AND ALCOHOL INDUCED LIVER DISEASE | KHK, GCK, FN3K | PDE4D 2514/4885ABCB1 4221/4885CYP3A4 1080/4885 |
| US-20250177348-A1 | Methods for Fructokinase Meditation of Alcohol Craving and Alcohol Induced Liver Disease | KHK, GCK, FN3K | PDE4D 1263/4885ABCB1 4298/4885CYP3A4 1789/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.