Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | F7 | P08709 | 3/20 | 0.47 |
| ▸ | F3 | P13726 | 3/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | OXER1 | Q8TDS5 | 2/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.47 |
| ▸ | PPARG | P37231 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | PPARD | Q03181 | 2/20 | 0.47 |
| ▸ | PPARA | Q07869 | 2/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13740227 | 0.87 | ALDH1A1 (0.53) | ALDH1A1F7F3CYP19A1MAPT | |
| SCHEMBL4023965 | 0.82 | ALDH1A1 (0.62) | ALDH1A1F7F3CYP19A1MAPT | |
| SCHEMBL29706306 | 0.82 | ALDH1A1 (0.62) | ALDH1A1F7F3CYP19A1MAPT | |
| SCHEMBL4023964 | 0.82 | ALDH1A1 (0.62) | ALDH1A1F7F3CYP19A1MAPT | |
| SCHEMBL16325232 | 0.81 | ALDH1A1 (0.47) | ALDH1A1F7F3CYP19A1MAPT | |
| SCHEMBL16822411 | 0.81 | EPHX2 (0.56) | ALDH1A1F7F3CYP19A1CYP3A4 | |
| SCHEMBL15253025 | 0.81 | CNR1 (0.64) | ALDH1A1F7F3CYP19A1MAPT | |
| SCHEMBL15253026 | 0.81 | CNR1 (0.64) | ALDH1A1F7F3CYP19A1MAPT | |
| SCHEMBL16822410 | 0.81 | EPHX2 (0.56) | ALDH1A1F7F3CYP19A1CYP3A4 | |
| SCHEMBL13741280 | 0.80 | ALDH1A1 (0.46) | ALDH1A1F7F3CYP19A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014204856-A1 | FATTY ACID ANTICANCER DERIVATIVES AND THEIR USES | CATABASIS PHARMACEUTICALS, INC. (US) | 2014-12-24 | — | — | WO | disclosed |