SCHEMBL1634159

SCHEMBL1634159

O=C(Oc1[c]cccc1)C12CC3CC(CC(C3)C1)C2

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.54
GAA P10253 2/20 0.53
MAPT P10636 1/20 0.53
XBP1 P17861 1/20 0.53
MEN1 O00255 3/20 0.48
KMT2A Q03164 3/20 0.48
ALDH1A1 P00352 4/20 0.44
TP53 P04637 3/20 0.44
ATM Q13315 2/20 0.44
POLB P06746 2/20 0.44
LMNA P02545 1/20 0.44
CNR2 P34972 1/20 0.41
CYP1A2 P05177 2/20 0.41
CYP2D6 P10635 2/20 0.41
CYP2C9 P11712 2/20 0.41
CYP2C19 P33261 2/20 0.41
HPGD P15428 2/20 0.41
CYP17A1 P05093 2/20 0.40
CYP19A1 P11511 2/20 0.40
RECQL P46063 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1634162 0.77 GAA (0.72) KDM4EGAAMAPTXBP1MEN1
SCHEMBL14651295 0.75 MAPT (0.86) KDM4EGAAMAPTXBP1MEN1
SCHEMBL11473992 0.74 GAA (0.68) KDM4EGAAMAPTXBP1MEN1
SCHEMBL22201 0.73
SCHEMBL676910 0.72 FAAH (0.30) CYP17A1CYP19A1
SCHEMBL29837014 0.71 KDM4E (0.67) KDM4EGAAMAPTXBP1MEN1
SCHEMBL13004874 0.70 KDM4E (0.66) KDM4EGAAMAPTXBP1MEN1
SCHEMBL13004858 0.70 MAPT (0.65) KDM4EGAAMAPTXBP1MEN1
SCHEMBL31337909 0.70 KDM4E (0.54) KDM4EGAAMAPTXBP1MEN1
SCHEMBL30924171 0.70 MAPT (0.65) KDM4EGAAMAPTXBP1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8378016-B2 Chemically amplified positive resist composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-02-19 US claimed
US-7932334-B2 Resin suitable for an acid generator SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-04-26 US claimed