Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.72 |
| ▸ | MAPT | P10636 | 1/20 | 0.72 |
| ▸ | XBP1 | P17861 | 1/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.67 |
| ▸ | TP53 | P04637 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14651295 | 0.90 | MAPT (0.86) | GAAMAPTXBP1KDM4ETP53 | |
| SCHEMBL5567915 | 0.89 | GAA (0.58) | GAAMAPTXBP1KDM4ETP53 | |
| SCHEMBL10170645 | 0.86 | GAA (0.63) | GAAMAPTXBP1KDM4ETP53 | |
| SCHEMBL5082277 | 0.85 | MAPT (0.53) | GAAMAPTXBP1KDM4ETP53 | |
| SCHEMBL5567903 | 0.85 | GAA (0.54) | GAAMAPTXBP1KDM4ETP53 | |
| SCHEMBL13004858 | 0.84 | MAPT (0.65) | GAAMAPTXBP1KDM4ETP53 | |
| SCHEMBL30924171 | 0.84 | MAPT (0.65) | GAAMAPTXBP1KDM4ETP53 | |
| SCHEMBL13255975 | 0.84 | GAA (1.00) | GAAMAPTXBP1KDM4ETP53 | |
| SCHEMBL13004855 | 0.82 | MAPT (0.73) | GAAMAPTXBP1KDM4ETP53 | |
| SCHEMBL11473992 | 0.82 | GAA (0.68) | GAAMAPTXBP1KDM4ETP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114890963-B | Benzylidene thiazolidinedione derivative, and preparation method and application thereof | 湖州师范学院 | 2023-05-05 | — | — | CN | claimed |
| CN-114890963-A | Benzylidene thiazolidinedione derivatives, and preparation method and application thereof | 湖州师范学院 | 2022-08-12 | — | — | CN | claimed |
| US-8378016-B2 | Chemically amplified positive resist composition | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-02-19 | — | — | US | claimed |
| US-7932334-B2 | Resin suitable for an acid generator | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-04-26 | — | — | US | claimed |
| CN-114890963-B | Benzylidene thiazolidinedione derivative, and preparation method and application thereof | 湖州师范学院 | 2023-05-05 | — | — | CN | disclosed |
| CN-114890963-A | Benzylidene thiazolidinedione derivatives, and preparation method and application thereof | 湖州师范学院 | 2022-08-12 | — | — | CN | disclosed |
| WO-2021262426-A2 | ADAMANTANE AMIDES AND THIOAMIDES FOR THE TREATMENT OF EBOLAVIRUS INFECTION | ARISAN THERAPEUTICS INC. (US) | 2021-12-30 | — | — | WO | disclosed |
| EP-3405183-A1 | ADAMATANE DERIVATIVES FOR THE TREATMENT OF FILOVIRUS INFECTION | Arisan Therapeutics Inc. (US) | 2018-11-28 | — | — | EP | disclosed |
| WO-2017127306-A1 | ADAMATANE DERIVATIVES FOR THE TREATMENT OF FILOVIRUS INFECTION | ARISAN THERAPEUTICS (US) | 2017-07-27 | — | — | WO | disclosed |