SCHEMBL163433

SCHEMBL163433

Nc1ncco1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9425516 0.97
Benzene SCHEMBL28179804 0.94 HSP90AA1 (0.36)
Pyrimidine SCHEMBL28940749 0.85 HSP90AA1 (0.34)
Formic Acid SCHEMBL3423113 0.85
Thiophene SCHEMBL27622194 0.83 ALDH1A1 (0.32)
Isoxazole SCHEMBL28638568 0.82 PARP1 (0.54)
SCHEMBL27667561 0.80 PTK2 (0.35)
SCHEMBL28165844 0.76
Serine SCHEMBL312921 0.73 ARG1 (0.37)
SCHEMBL4300474 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2751 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3723744-B1 C5AR INHIBITORS FOR USE IN THE TREATMENT OF CHEMOTHERAPY-INDUCED IATROGENIC PAIN DOMPE FARM SPA (IT) 2026-03-18 EP claimed
WO-2025086243-A1 LEUKOCYTE RECEPTOR TYROSINE KINASE INHIBITOR 深圳湾实验室坪山生物医药研发转化中心 2025-05-01 WO claimed
CN-119805886-A Film stripping liquid and preparation method thereof 湖北兴福电子材料股份有限公司 2025-04-11 CN claimed
CN-119701000-A Polypeptide coupling medicine, and preparation method and application thereof 中国人民解放军空军军医大学 2025-03-28 CN claimed
CN-117924682-B Preparation method of aging-resistant polylactic acid material and aging-resistant polylactic acid material 深圳市久信达科技有限公司 2025-03-25 CN claimed
CN-119674110-A Heteroatom doped asymmetric coordination structure oxygen reduction catalyst and preparation method and application thereof 海南大学 2025-03-21 CN claimed
US-20250066570-A1 LAMINATE DEVICE WITH METALLIC AND POLYMER LAYERS QUANTUM MICROMATERIALS INC (US) 2025-02-27 US claimed
WO-2025013869-A1 FLUORINE-CONTAINING POLYMER HAVING NITROGEN-CONTAINING AROMATIC RING, PRODUCTION METHOD THEREFOR, AND COMPOSITION THEREOF ダイキン工業株式会社 2025-01-16 WO claimed
CN-118140931-A Application of chromene-thiazole/oxazolamine compound 贵州医科大学 2024-06-07 CN claimed
CN-118029982-A Oil extraction method for multi-medium displacement and throughput linkage of heavy oil reservoir 中国石油天然气股份有限公司 2024-05-14 CN claimed
US-4948898-A MICROBIOCIDE DERIVATIVES HOFFMANN-LA ROCHE INC. (US) 1990-08-14 US claimed
US-4904676-A DOPAMINE AGONIST; NERVOUS SYSTEM AND CARDIOVASCULAR DISORDERS AKZO N.V. (NL) 1990-02-27 US claimed
EP-0005732-B1 Use of 2-amino-oxazolo- or 2-amino-thiazolo-[5,4-d]azepines and acid-addition salts thereof for the manufacture of a medicament for the treatment of Angina Pectoris Dr. Karl Thomae GmbH (DE) 1988-06-15 EP claimed
EP-0248399-A1 Aminoazole derivatives and their production and use SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) 1987-12-09 EP claimed
EP-0244018-A1 Amino-thiazole and oxazole derivatives AKZO N.V. (NL) 1987-11-04 EP claimed
EP-0201459-A1 Acylaminomethyl-penem compounds, their preparation and pharmaceutical formulations containing them CIBA-GEIGY AG (CH) 1986-11-12 EP claimed
EP-0143746-A2 5-Amino 4-hydroxy-valeryl-substituted derivatives CIBA-GEIGY AG (CH) 1985-06-05 EP claimed
US-4507477-A CYCLIZATION RIKER LABORATORIES, INC. (US) 1985-03-26 US claimed
EP-0121499-A2 Cephalosporins, their preparation and pharmaceutical compositions CIBA-GEIGY AG (CH) 1984-10-10 EP claimed
US-4242495-A COATINGS, MOLDINGS, FOAMS THE FIRESTONE TIRE & RUBBER COMPANY (US) 1980-12-30 US claimed