Histidine

Histidine

SCHEMBL163442

NC(Cc1c[nH]cn1)C(=O)O.NC(Cc1c[nH]cn1)C(=O)O

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 3/20 0.47
CYP3A4 P08684 2/20 0.47
CYP1A2 P05177 1/20 0.46
PKM P14618 2/20 0.43
ALPI P09923 1/20 0.43
PTGS1 P23219 1/20 0.43
XIAP P98170 1/20 0.43
GRIA2 P42262 5/20 0.41
GRIA1 P42261 4/20 0.41
GRIA3 P42263 4/20 0.41
GRIA4 P48058 4/20 0.41
HSD17B10 Q99714 2/20 0.40
KDM4E B2RXH2 2/20 0.40
MEN1 O00255 2/20 0.40
LMNA P02545 2/20 0.40
MAPT P10636 2/20 0.40
BLM P54132 2/20 0.40
PMP22 Q01453 2/20 0.40
KMT2A Q03164 2/20 0.40
HIF1A Q16665 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Histidine SCHEMBL8316642 1.00 SLC7A5 (0.47) SLC7A5CYP3A4CYP1A2PKMALPI
Histidine SCHEMBL8080341 1.00 SLC7A5 (0.47) SLC7A5CYP3A4CYP1A2PKMALPI
Histidine SCHEMBL388561 1.00 SLC7A5 (0.47) SLC7A5CYP3A4CYP1A2PKMALPI
Histidine SCHEMBL18824897 1.00 SLC7A5 (0.47) SLC7A5CYP3A4CYP1A2PKMALPI
Histidine SCHEMBL388563 1.00 SLC7A5 (0.47) SLC7A5CYP3A4CYP1A2PKMALPI
Histidine SCHEMBL995910 1.00 SLC7A5 (0.47) SLC7A5CYP3A4CYP1A2PKMALPI
Histidine SCHEMBL3258 1.00 SLC7A5 (0.47) SLC7A5CYP3A4CYP1A2PKMALPI
Histidine SCHEMBL163443 1.00 SLC7A5 (0.47) SLC7A5CYP3A4CYP1A2PKMALPI
Histidine SCHEMBL3259 1.00 SLC7A5 (0.47) SLC7A5CYP3A4CYP1A2PKMALPI
Histidine SCHEMBL29500208 1.00 SLC7A5 (0.47) SLC7A5CYP3A4CYP1A2PKMALPI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101781325-A Gallium salicylaldehyde amino acid Schiff base quaternary coordination compound, preparation method and application thereof UNIV BEIJING NORMAL 2010-07-21 CN claimed
CN-1325063-C L-amino acid water-soluble pearl powder and its preparing method SONG TINGSHENG (CN) 2007-07-11 CN claimed
CN-1709282-A L-amino acid water-soluble pearl powder and its preparing method SONG TINGSHENG (CN) 2005-12-21 CN claimed
CN-115315195-B Hydroxy-and methoxy-substituted flavonoids and use thereof 弗门尼舍有限公司 2024-07-02 CN disclosed
CN-115315194-B Hydroxy-and methoxy-substituted flavones and use thereof 弗门尼舍有限公司 2024-06-21 CN disclosed
CN-115938594-A Method for predicting spontaneous abortion by integrating learning and combining pre-pregnancy serum metabolome 上海市第一妇婴保健院 2023-04-07 CN disclosed
CN-114008452-A Method for evaluating food related to cognitive function 味之素株式会社 2022-02-01 CN disclosed
US-20210393779-A1 ACTIVIN A ANTIBODY FORMULATIONS AND METHODS OF USE THEREOF REGENERON PHARMACEUTICALS, INC. 2021-12-23 US disclosed
CN-113308122-A Degradable protein plastic and preparation method thereof 清华大学 2021-08-27 CN disclosed
WO-2021113739-A1 FORMULATIONS OF ANTI-CD38 ANTIBODIES FOR SUBCUTANEOUS ADMINISTRATION BALLET THOMAS (US) 2021-06-10 WO disclosed
CN-108424861-B Streptomyces iranantensis and application thereof 中国热带农业科学院热带生物技术研究所 2021-06-04 CN disclosed
EP-1552303-A4 BIOSENSOR UNIV DUKE (US) 2006-12-27 EP disclosed
CN-1709282-A L-amino acid water-soluble pearl powder and its preparing method SONG TINGSHENG (CN) 2005-12-21 CN disclosed
CN-1227993-C Soy sauce and its preparation method LUYIKANG BIOLOGY SCIENCE AND T (CN) 2005-11-23 CN disclosed
EP-1553914-A2 NOVEL COSMETIC FORMULATIONS BASED ON A GEL-FORMING AND/OR THICKENING AGENT AND APPLICATIONS OF SAME Lucas Meyer Cosmetics (FR) 2005-07-20 EP disclosed
EP-1552303-A2 BIOSENSOR DUKE UNIVERSITY (US) 2005-07-13 EP disclosed
CN-1511473-A Soy sauce and its preparation method 绿益康生物科技实业股份有限公司 2004-07-14 CN disclosed
WO-2004036176-A2 BIOSENSOR DUKE UNIVERSITY (US) 2004-04-29 WO disclosed
WO-2004030605-A2 COSMETIC FORMULATIONS BASED ON A GEL-FORMING AND/OR THICKENING AGENT AND APPLICATIONS OF SAME LUCAS MEYER COSMETICS (FR) 2004-04-15 WO disclosed
CN-85101341-A Preparation of high purity protein and its application 1987-01-31 CN disclosed