Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMT1 | P30419 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4455156 | 0.79 | GPR35 (0.36) | — | |
| SCHEMBL27707789 | 0.72 | MAOB (0.38) | — | |
| SCHEMBL28730227 | 0.72 | — | — | |
| SCHEMBL5546147 | 0.72 | ALDH1A1 (0.32) | — | |
| SCHEMBL5539069 | 0.71 | AHR (0.41) | — | |
| SCHEMBL533234 | 0.67 | CYP1A2 (0.38) | — | |
| SCHEMBL14741951 | 0.65 | NMT1 (0.32) | NMT1 | |
| SCHEMBL28543935 | 0.64 | NMT1 (0.32) | NMT1 | |
| SCHEMBL6089630 | 0.64 | TSHR (0.32) | — | |
| SCHEMBL16597469 | 0.64 | CYP3A4 (0.35) | NMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108440515-B | Substituted benzofuranyl and benzoxazolyl compounds and uses thereof | 卡尔约药物治疗公司 | 2022-05-03 | — | — | CN | disclosed |
| EP-3016946-A1 | SUBSTITUTED BENZOFURANYL AND BENZOXAZOLYL COMPOUNDS AND USES THEREOF | Karyopharm Therapeutics, Inc. (US) | 2016-05-11 | — | — | EP | disclosed |
| WO-2015003166-A1 | SUBSTITUTED BENZOFURANYL AND BENZOXAZOLYL COMPOUNDS AND USES THEREOF | Karyopharm Therapeutics Inc. (US) | 2015-01-08 | — | — | WO | disclosed |