Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 5/20 | 0.41 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | CASP3 | P42574 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | CDK9 | P50750 | 1/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16348379 | 0.74 | EPHX2 (0.44) | EPHX2PIM1IDO1CA1CA2 | |
| SCHEMBL13522796 | 0.72 | KDM6B (0.73) | KDM4ENPC1CASP3RAB9ASENP8 | |
| SCHEMBL5534902 | 0.72 | KDM4E (0.59) | KDM4ENPC1RAB9AALDH1A1LMNA | |
| SCHEMBL5536101 | 0.70 | NPC1 (0.53) | SLC9A1NPC1RAB9AALDH1A1NFKB1 | |
| SCHEMBL9863203 | 0.70 | SNCA (0.46) | NPC1RAB9AMAPT | |
| SCHEMBL6762328 | 0.70 | MAOA (0.48) | EPHX2CA1CA2KDM4ENPC1 | |
| SCHEMBL31093991 | 0.70 | HSD17B10 (0.62) | EPHX2PIM1IDO1CA1CA2 | |
| SCHEMBL6242615 | 0.70 | HSD17B10 (0.62) | EPHX2PIM1IDO1CA1CA2 | |
| SCHEMBL5539532 | 0.69 | TP53 (0.55) | KDM4ENPC1CASP3RAB9ASENP8 | |
| SCHEMBL6510628 | 0.69 | IDO1 (0.51) | EPHX2PIM1IDO1KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7642358-B2 | Substituted phenylacetic acids | METABOLEX, INC. (US) | 2010-01-05 | — | — | US | disclosed |
| US-7642358-B2 | Substituted phenylacetic acids | METABOLEX, INC. (US) | 2010-01-05 | — | — | US | disclosed |