Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 10/20 | 0.43 |
| ▸ | ESR1 | P03372 | 9/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.43 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.42 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9705710 | 0.80 | CA1 (0.48) | MAPTESR2ESR1NPC1RAB9A | |
| SCHEMBL9863217 | 0.80 | ESR1 (0.54) | SNCAMAPTESR2ESR1HSD17B1 | |
| SCHEMBL12568356 | 0.79 | ALOX5 (0.48) | SNCAMAPTESR2ESR1 | |
| SCHEMBL9862893 | 0.78 | NPC1 (0.51) | MAPTESR2ESR1NPC1RAB9A | |
| SCHEMBL3590075 | 0.76 | HDAC6 (0.47) | MAPTESR2ESR1HSD17B1HSD17B2 | |
| SCHEMBL11320611 | 0.74 | NPC1 (0.59) | SNCAMAPTESR2ESR1NPC1 | |
| SCHEMBL16072944 | 0.74 | CYP1A2 (0.58) | MAPTTP53MEN1KMT2A | |
| SCHEMBL2706143 | 0.74 | NPC1 (0.52) | MAPTNPC1RAB9ATP53MEN1 | |
| SCHEMBL272034 | 0.72 | HSD17B1 (0.68) | MAPTESR2ESR1FGFR1HSD17B1 | |
| SCHEMBL29696046 | 0.72 | HSD17B1 (0.68) | MAPTESR2ESR1FGFR1HSD17B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5002960-A | Viricides for combating picornaviruses | STERLING DRUG, INC. (US) | 1991-03-26 | — | — | US | disclosed |
| US-4939267-A | Viricides | STERLING DRUG INC. (US) | 1990-07-03 | — | — | US | disclosed |
| US-4843087-A | OXAZOLINYL COMPOUNDS; RHINOVIRUSES AND PICORNAVIRUSES | STERLING DRUG INC. (US) | 1989-06-27 | — | — | US | disclosed |