Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.58 |
| ▸ | PPARA | Q07869 | 5/20 | 0.58 |
| ▸ | TSPO | P30536 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16348410 | 0.95 | PPARG (0.59) | PPARGPPARATSPOALDH1A1NPSR1 | |
| SCHEMBL16348406 | 0.90 | PPARA (0.46) | PPARGPPARATSPOALDH1A1NPSR1 | |
| SCHEMBL13374081 | 0.89 | PPARG (0.63) | PPARGPPARATSPOALDH1A1NPSR1 | |
| SCHEMBL13374080 | 0.89 | PPARG (0.63) | PPARGPPARATSPOALDH1A1NPSR1 | |
| SCHEMBL5644684 | 0.89 | PPARG (0.63) | PPARGPPARATSPOALDH1A1NPSR1 | |
| SCHEMBL13523120 | 0.88 | PPARG (0.60) | PPARGPPARATSPOALDH1A1NPSR1 | |
| SCHEMBL16348411 | 0.86 | PPARG (0.54) | PPARGPPARAPKMHTR2CHTR2B | |
| SCHEMBL13523114 | 0.86 | PPARG (0.51) | PPARGPPARATSPOALDH1A1NPSR1 | |
| SCHEMBL13523102 | 0.84 | PPARG (0.54) | PPARGPPARATSPOALDH1A1NPSR1 | |
| SCHEMBL13522950 | 0.84 | ALDH1A1 (0.57) | PPARGPPARAALDH1A1NPSR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7642358-B2 | Substituted phenylacetic acids | METABOLEX, INC. (US) | 2010-01-05 | — | — | US | disclosed |
| US-7642358-B2 | Substituted phenylacetic acids | METABOLEX, INC. (US) | 2010-01-05 | — | — | US | disclosed |