Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.46 |
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | TSPO | P30536 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | F9 | P00740 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13523147 | 0.91 | PPARG (0.49) | PPARAPPARGALDH1A1NPSR1L3MBTL1 | |
| SCHEMBL16348349 | 0.90 | PPARG (0.58) | PPARAPPARGALDH1A1NPSR1L3MBTL1 | |
| SCHEMBL16348410 | 0.85 | PPARG (0.59) | PPARAPPARGALDH1A1NPSR1L3MBTL1 | |
| SCHEMBL16348330 | 0.83 | TSPO (0.59) | PPARAPPARGALDH1A1NPSR1L3MBTL1 | |
| SCHEMBL13523097 | 0.82 | ALDH1A1 (0.42) | PPARAPPARGALDH1A1NPSR1L3MBTL1 | |
| SCHEMBL10621819 | 0.81 | TSHR (0.56) | PPARAPPARGALDH1A1NPSR1L3MBTL1 | |
| SCHEMBL13523136 | 0.81 | KDM4E (0.48) | PPARAPPARGALDH1A1NPSR1L3MBTL1 | |
| SCHEMBL13374080 | 0.79 | PPARG (0.63) | PPARAPPARGALDH1A1NPSR1L3MBTL1 | |
| SCHEMBL13374081 | 0.79 | PPARG (0.63) | PPARAPPARGALDH1A1NPSR1L3MBTL1 | |
| SCHEMBL5644684 | 0.79 | PPARG (0.63) | PPARAPPARGALDH1A1NPSR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7642358-B2 | Substituted phenylacetic acids | METABOLEX, INC. (US) | 2010-01-05 | — | — | US | disclosed |
| US-7642358-B2 | Substituted phenylacetic acids | METABOLEX, INC. (US) | 2010-01-05 | — | — | US | disclosed |