Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSPO | P30536 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 5/20 | 0.44 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | HTR2B | P41595 | 2/20 | 0.39 |
| ▸ | HTR6 | P50406 | 2/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16348430 | 0.87 | PPARG (0.56) | TSPOPPARGSLC22A12SLC6A4HTR2C | |
| SCHEMBL13523145 | 0.85 | PPARG (0.42) | PPARGSLC22A12SLC6A4 | |
| SCHEMBL16348326 | 0.80 | PPARG (0.41) | PPARGSLC22A12SLC6A4HTR2CHTR2B | |
| SCHEMBL4576171 | 0.78 | PNMT (0.42) | PPARGSLC22A12MRGPRX4 | |
| SCHEMBL16348320 | 0.78 | PPARG (0.40) | PPARGSLC22A12SLC6A4 | |
| SCHEMBL16348368 | 0.77 | PPARG (0.38) | PPARGSLC22A12SLC6A4HTR2CHTR2B | |
| SCHEMBL13881955 | 0.76 | PPARG (0.43) | PPARGSLC22A12SLC6A4 | |
| SCHEMBL16348411 | 0.76 | PPARG (0.54) | PPARGSLC22A12SLC6A4HTR2CHTR2B | |
| SCHEMBL13522968 | 0.76 | KDM4E (0.42) | TSPOPPARGSLC22A12MRGPRX4 | |
| SCHEMBL13374099 | 0.75 | PPARG (0.72) | PPARGSLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7642358-B2 | Substituted phenylacetic acids | METABOLEX, INC. (US) | 2010-01-05 | — | — | US | disclosed |
| US-7642358-B2 | Substituted phenylacetic acids | METABOLEX, INC. (US) | 2010-01-05 | — | — | US | disclosed |