Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.38 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16348326 | 0.93 | PPARG (0.41) | PPARGSLC22A12SLC6A4MAPTLMNA | |
| SCHEMBL16348313 | 0.92 | PPARG (0.44) | PPARGSLC22A12SLC6A4HTR2CHTR2B | |
| SCHEMBL16348426 | 0.86 | PSEN1 (0.38) | PPARGMAPTLMNASMN1; SMN2 | |
| SCHEMBL16348352 | 0.84 | PPARG (0.48) | PPARGSLC22A12SLC6A4HTR2CHTR2B | |
| SCHEMBL16348341 | 0.83 | JMJD6 (0.39) | PPARGSLC22A12SLC6A4MAPTLMNA | |
| SCHEMBL16348342 | 0.83 | NPC1 (0.41) | PPARGMAPTSMN1; SMN2ELANEADORA1 | |
| SCHEMBL16348339 | 0.81 | PPARG (0.39) | PPARGMAPTLMNA | |
| SCHEMBL16348367 | 0.81 | JMJD6 (0.39) | MAPTSMN1; SMN2ELANEADORA1 | |
| SCHEMBL16348369 | 0.80 | PPARA (0.48) | PPARG | |
| SCHEMBL16348360 | 0.79 | JMJD6 (0.42) | PPARGMAPTLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7642358-B2 | Substituted phenylacetic acids | METABOLEX, INC. (US) | 2010-01-05 | — | — | US | disclosed |
| US-7642358-B2 | Substituted phenylacetic acids | METABOLEX, INC. (US) | 2010-01-05 | — | — | US | disclosed |