Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 10/20 | 0.43 |
| ▸ | PPARA | Q07869 | 6/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | CTSA | P10619 | 1/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.35 |
| ▸ | MPO | P05164 | 1/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16348375 | 0.92 | PPARG (0.45) | PPARGPPARASLC6A4CTSASLC22A12 | |
| SCHEMBL16348345 | 0.91 | PPARA (0.41) | PPARGPPARACTSA | |
| SCHEMBL16348344 | 0.90 | PPARG (0.43) | PPARGPPARASLC6A4CTSASLC22A12 | |
| SCHEMBL16348377 | 0.89 | PPARA (0.47) | PPARGPPARA | |
| SCHEMBL16348401 | 0.86 | PPARG (0.47) | PPARGPPARA | |
| SCHEMBL16348442 | 0.81 | PPARA (0.44) | PPARGPPARA | |
| SCHEMBL16348402 | 0.81 | PPARA (0.37) | PPARGPPARA | |
| SCHEMBL16348440 | 0.81 | PPARA (0.41) | PPARGPPARACTSA | |
| SCHEMBL16348390 | 0.80 | PPARA (0.49) | PPARGPPARACTSA | |
| SCHEMBL16348384 | 0.79 | PPARG (0.48) | PPARGPPARASLC6A4CTSAMPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7642358-B2 | Substituted phenylacetic acids | METABOLEX, INC. (US) | 2010-01-05 | — | — | US | disclosed |
| US-7642358-B2 | Substituted phenylacetic acids | METABOLEX, INC. (US) | 2010-01-05 | — | — | US | disclosed |