Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.48 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | CTSA | P10619 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.40 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | HTR2B | P41595 | 2/20 | 0.40 |
| ▸ | HTR6 | P50406 | 2/20 | 0.40 |
| ▸ | MPO | P05164 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16348407 | 0.88 | PPARA (0.54) | PPARGPPARACTSAHTR2CHTR2B | |
| SCHEMBL13522842 | 0.85 | PPARG (0.48) | PPARGPPARAMPOMAPT | |
| SCHEMBL16348405 | 0.84 | PPARG (0.53) | PPARGPPARACTSAHTR2CHTR2B | |
| SCHEMBL16348375 | 0.80 | PPARG (0.45) | PPARGPPARACTSASLC6A4MPO | |
| SCHEMBL13522929 | 0.79 | PPARG (0.52) | PPARGPPARACTSASLC6A4HTR2C | |
| SCHEMBL16348344 | 0.79 | PPARG (0.43) | PPARGPPARACTSASLC6A4HTR2C | |
| SCHEMBL16348441 | 0.79 | PPARG (0.43) | PPARGPPARACTSASLC6A4MPO | |
| SCHEMBL13523015 | 0.78 | APLNR (0.42) | PPARGCTSAMAPT | |
| SCHEMBL13522834 | 0.78 | PPARG (0.45) | PPARGPPARAMAPT | |
| SCHEMBL13522857 | 0.78 | PPARG (0.45) | PPARGPPARAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7642358-B2 | Substituted phenylacetic acids | METABOLEX, INC. (US) | 2010-01-05 | — | — | US | disclosed |
| US-7642358-B2 | Substituted phenylacetic acids | METABOLEX, INC. (US) | 2010-01-05 | — | — | US | disclosed |