Known targets — ChEMBL curated mechanism
PPARDPTGS1PTGS2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Lysine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lysine SCHEMBL9839931 | 1.00 | GSR (0.36) | GSRSLC7A5 | |
| Lysine SCHEMBL9679963 | 0.94 | GSR (0.34) | GSRSLC7A5 | |
| Lysine SCHEMBL10862298 | 0.87 | GSR (0.48) | GSRSLC7A5 | |
| Lysine SCHEMBL10862827 | 0.87 | GSR (0.48) | GSRSLC7A5 | |
| Lysine SCHEMBL9681209 | 0.83 | GSR (0.43) | GSRSLC7A5 | |
| Lysine SCHEMBL9839934 | 0.83 | GSR (0.43) | GSRSLC7A5 | |
| Lysine SCHEMBL9598249 | 0.81 | GSR (0.54) | GSRSLC7A5 | |
| Lysine SCHEMBL9598281 | 0.81 | GSR (0.54) | GSRSLC7A5 | |
| SCHEMBL16225105 | 0.81 | GSR (0.50) | GSRSLC7A5 | |
| Leucine SCHEMBL7557530 | 0.81 | GSR (0.50) | GSRSLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5112737-A | Binding proteins | APPLIED BIOTECHNOLOGY, INC. (US) | 1992-05-12 | — | — | US | disclosed |