Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AADAT | Q8N5Z0 | 13/20 | 0.64 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16348700 | 0.84 | AADAT (0.64) | AADATCA12CA9 | |
| SCHEMBL15493549 | 0.80 | AADAT (0.77) | AADATCA12CA9TSHR | |
| SCHEMBL14052940 | 0.79 | AADAT (1.00) | AADAT | |
| SCHEMBL9912456 | 0.77 | AADAT (0.62) | AADATRIPK1 | |
| SCHEMBL16348707 | 0.71 | AADAT (0.62) | AADATTSHRRIPK1 | |
| SCHEMBL14053143 | 0.69 | AADAT (0.62) | AADATTSHRRIPK1 | |
| SCHEMBL14053208 | 0.68 | AADAT (0.66) | AADATTSHR | |
| SCHEMBL9912473 | 0.67 | AADAT (1.00) | AADAT | |
| SCHEMBL3774144 | 0.66 | KMT2A (0.34) | AADATRIPK1 | |
| SCHEMBL9912477 | 0.66 | AADAT (1.00) | AADAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8933095-B2 | KAT II inhibitors | PFIZER INC. (US) | 2015-01-13 | — | — | US | disclosed |