Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AADAT | Q8N5Z0 | 13/20 | 0.62 |
| ▸ | RIPK1 | Q13546 | 4/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | STAT6 | P42226 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9912514 | 0.77 | AADAT (1.00) | AADAT | |
| SCHEMBL9912518 | 0.76 | AADAT (0.60) | AADATRIPK1ALDH1A1 | |
| SCHEMBL3774144 | 0.76 | KMT2A (0.34) | AADATRIPK1GAA | |
| SCHEMBL14136631 | 0.75 | AADAT (0.71) | AADATRIPK1HTR2CTSHR | |
| SCHEMBL16348700 | 0.75 | AADAT (0.64) | AADAT | |
| SCHEMBL14053143 | 0.73 | AADAT (0.62) | AADATRIPK1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL14053208 | 0.73 | AADAT (0.66) | AADATALDH1A1CYP1A2CYP3A4GAA | |
| SCHEMBL16348706 | 0.71 | AADAT (0.64) | AADATRIPK1TSHR | |
| SCHEMBL4897407 | 0.68 | CYP1A2 (0.39) | RIPK1ALDH1A1CYP1A2CYP3A4GAA | |
| SCHEMBL4889310 | 0.67 | RIPK1 (0.41) | RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8933095-B2 | KAT II inhibitors | PFIZER INC. (US) | 2015-01-13 | — | — | US | disclosed |