Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 0.34 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14253920 | 0.77 | RORC (0.32) | CYP3A4CYP17A1RORC | |
| SCHEMBL14253919 | 0.72 | RORC (0.33) | CYP3A4CYP17A1RORC | |
| SCHEMBL13813431 | 0.71 | CYP3A4 (0.34) | CYP3A4CYP17A1IDO1RORC | |
| SCHEMBL14253917 | 0.71 | CYP17A1 (0.34) | CYP3A4CYP17A1IDO1RORC | |
| SCHEMBL25289009 | 0.67 | CYP17A1 (0.43) | CYP3A4CYP17A1IDO1RORC | |
| SCHEMBL13813446 | 0.64 | TSHR (0.34) | — | |
| SCHEMBL21573048 | 0.63 | RORC (0.37) | CYP3A4CYP17A1RORC | |
| SCHEMBL21719301 | 0.63 | TBXAS1 (0.35) | CYP3A4CYP17A1RORC | |
| SCHEMBL22388552 | 0.63 | TBXAS1 (0.35) | CYP3A4CYP17A1RORC | |
| SCHEMBL24092913 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7342016-B2 | Farnesyl protein transferase inhibitors as antitumor agents | SCHERING CORPORATION (US) | 2008-03-11 | — | — | US | disclosed |