Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGA | O60502 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 8/20 | 0.33 |
| ▸ | CA2 | P00918 | 8/20 | 0.33 |
| ▸ | CA9 | Q16790 | 8/20 | 0.33 |
| ▸ | CA12 | O43570 | 6/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 6/20 | 0.33 |
| ▸ | BCHE | P06276 | 2/20 | 0.33 |
| ▸ | GALR3 | O60755 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | CD69 | Q07108 | 1/20 | 0.32 |
| ▸ | PRKCA | P17252 | 1/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14036675 | 0.88 | LMNA (0.34) | LMNAALDH1A1TP53MAPTTDP1 | |
| SCHEMBL12154623 | 0.85 | CD69 (0.44) | LMNAALDH1A1TP53MAPTTDP1 | |
| SCHEMBL12150456 | 0.85 | LMNA (0.40) | LMNAALDH1A1TP53MAPTTDP1 | |
| SCHEMBL12879162 | 0.85 | LMNA (0.40) | LMNAALDH1A1TP53MAPTTDP1 | |
| SCHEMBL1377520 | 0.84 | LMNA (0.51) | LMNAALDH1A1TP53MAPTTDP1 | |
| SCHEMBL13614200 | 0.84 | LMNA (0.51) | LMNAALDH1A1TP53MAPTTDP1 | |
| SCHEMBL15031303 | 0.84 | LMNA (0.51) | LMNAALDH1A1TP53MAPTTDP1 | |
| SCHEMBL12892515 | 0.84 | LMNA (0.51) | LMNAALDH1A1TP53MAPTTDP1 | |
| SCHEMBL12150506 | 0.73 | KMT2A (0.37) | ALDH1A1MAPTCA1CA2CA9 | |
| SCHEMBL12300558 | 0.71 | LMNA (0.36) | LMNAALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7429565-B2 | Antiviral phosphonate analogs | GILEAD SCIENCES, INC. (US) | 2008-09-30 | — | — | US | disclosed |