Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.66 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.66 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 9/20 | 0.43 |
| ▸ | NPC1 | O15118 | 9/20 | 0.43 |
| ▸ | RAB9A | P51151 | 6/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.43 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.43 |
| ▸ | CD74 | P04233 | 1/20 | 0.43 |
| ▸ | MIF | P14174 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12725749 | 1.00 | MAPT (0.66) | MAPTALDH1A1PLA2G1BATG4BKDM4E | |
| SCHEMBL12725753 | 0.81 | KDM4E (0.61) | MAPTALDH1A1KDM4EPOLBKMT2A | |
| SCHEMBL1635307 | 0.81 | KDM4E (0.61) | MAPTALDH1A1KDM4EPOLBKMT2A | |
| SCHEMBL16077906 | 0.80 | ALDH1A1 (0.70) | MAPTALDH1A1PLA2G1BATG4BKDM4E | |
| SCHEMBL1635902 | 0.76 | KDM4E (0.67) | MAPTALDH1A1KDM4EPOLBKMT2A | |
| SCHEMBL12725750 | 0.76 | KDM4E (0.67) | MAPTALDH1A1KDM4EPOLBKMT2A | |
| SCHEMBL23335111 | 0.76 | KDM4E (0.67) | MAPTALDH1A1KDM4EPOLBKMT2A | |
| SCHEMBL1634513 | 0.74 | KDM4E (0.63) | MAPTALDH1A1KDM4EPOLBKMT2A | |
| SCHEMBL12725741 | 0.74 | KDM4E (0.63) | MAPTALDH1A1KDM4EPOLBKMT2A | |
| SCHEMBL6721105 | 0.74 | KDM4E (0.77) | MAPTALDH1A1KDM4EPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7932331-B2 | Polymerisation of ethylene and α-olefins with imino-quinolinol complexes | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2011-04-26 | — | — | US | disclosed |
| EP-1994006-B1 | POLYMERISATION OF ETHYLENE AND ALPHA-OLEFINS WITH IMINO-QUINOLINOL COMPLEXES | TOTAL PETROCHEMICALS RES FELUY (BE) | 2010-11-17 | — | — | EP | disclosed |
| US-20100004411-A1 | POLYMERISATION OF ETHYLENE AND ALPHA-OLEFINS WITH IMINO-QUINOLINOL COMPLEXES | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2010-01-07 | — | — | US | disclosed |
| EP-1832579-A1 | Polymerisation of ethylene and alpha-olefins with imino-quinolinol complexes | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2007-09-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100004411-A1 | POLYMERISATION OF ETHYLENE AND ALPHA-OLEFINS WITH IMINO-QUINOLINOL COMPLEXES | UBE2L3, PCNA, UBE2L6 | MAPT 1104/4885ALDH1A1 2024/4885PLA2G1B 3227/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.