Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.51 |
| ▸ | MEN1 | O00255 | 9/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | ATM | Q13315 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | DHODH | Q02127 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.47 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.47 |
| ▸ | CD74 | P04233 | 1/20 | 0.47 |
| ▸ | MIF | P14174 | 1/20 | 0.47 |
| ▸ | TDP2 | O95551 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12725753 | 1.00 | KDM4E (0.61) | KDM4EL3MBTL1POLBMAPTKMT2A | |
| SCHEMBL1634970 | 0.81 | MAPT (0.66) | KDM4EPOLBMAPTKMT2AMEN1 | |
| SCHEMBL12725749 | 0.81 | MAPT (0.66) | KDM4EPOLBMAPTKMT2AMEN1 | |
| SCHEMBL1635902 | 0.81 | KDM4E (0.67) | KDM4EPOLBMAPTKMT2AMEN1 | |
| SCHEMBL12725750 | 0.81 | KDM4E (0.67) | KDM4EPOLBMAPTKMT2AMEN1 | |
| SCHEMBL14280792 | 0.80 | L3MBTL1 (0.54) | KDM4EL3MBTL1POLBMAPTKMT2A | |
| SCHEMBL6721105 | 0.78 | KDM4E (0.77) | KDM4EL3MBTL1POLBMAPTKMT2A | |
| SCHEMBL4454891 | 0.77 | KDM4E (1.00) | KDM4EL3MBTL1POLBMAPTKMT2A | |
| SCHEMBL4454893 | 0.77 | KDM4E (1.00) | KDM4EL3MBTL1POLBMAPTKMT2A | |
| SCHEMBL1635015 | 0.77 | KDM4E (0.53) | KDM4EL3MBTL1POLBMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7932331-B2 | Polymerisation of ethylene and α-olefins with imino-quinolinol complexes | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2011-04-26 | — | — | US | disclosed |
| EP-1994006-B1 | POLYMERISATION OF ETHYLENE AND ALPHA-OLEFINS WITH IMINO-QUINOLINOL COMPLEXES | TOTAL PETROCHEMICALS RES FELUY (BE) | 2010-11-17 | — | — | EP | disclosed |
| US-20100004411-A1 | POLYMERISATION OF ETHYLENE AND ALPHA-OLEFINS WITH IMINO-QUINOLINOL COMPLEXES | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2010-01-07 | — | — | US | disclosed |
| EP-1832579-A1 | Polymerisation of ethylene and alpha-olefins with imino-quinolinol complexes | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2007-09-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100004411-A1 | POLYMERISATION OF ETHYLENE AND ALPHA-OLEFINS WITH IMINO-QUINOLINOL COMPLEXES | UBE2L3, PCNA, UBE2L6 | KDM4E 3956/4885L3MBTL1 3862/4885POLB 165/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.