Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ACHE | P22303 | 4/20 | 0.34 |
| ▸ | BCHE | P06276 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4145325 | 0.78 | NOS3 (0.42) | NOS3NOS1NOS2TRPA1SIGMAR1 | |
| Oxindole SCHEMBL9305641 | 0.76 | NOS3 (0.43) | NOS3NOS1NOS2TRPA1SIGMAR1 | |
| SCHEMBL4183978 | 0.71 | NOS3 (0.43) | NOS3NOS1NOS2TRPA1SIGMAR1 | |
| SCHEMBL5100916 | 0.71 | NOS3 (0.43) | NOS3NOS1NOS2TRPA1SIGMAR1 | |
| SCHEMBL5021700 | 0.70 | NOS3 (0.46) | NOS3NOS1NOS2TRPA1SIGMAR1 | |
| SCHEMBL28065256 | 0.69 | NOS3 (0.45) | NOS3NOS1NOS2TRPA1SIGMAR1 | |
| SCHEMBL35438 | 0.67 | NOS3 (0.48) | NOS3NOS1NOS2TRPA1SIGMAR1 | |
| SCHEMBL11780213 | 0.67 | NOS3 (0.43) | NOS3NOS1NOS2TRPA1SIGMAR1 | |
| SCHEMBL47849 | 0.67 | NOS3 (0.43) | NOS3NOS1NOS2TRPA1SIGMAR1 | |
| SCHEMBL3616940 | 0.67 | NOS3 (0.48) | NOS3NOS1NOS2TRPA1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7932331-B2 | Polymerisation of ethylene and α-olefins with imino-quinolinol complexes | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2011-04-26 | — | — | US | disclosed |
| US-7932331-B2 | Polymerisation of ethylene and α-olefins with imino-quinolinol complexes | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2011-04-26 | — | — | US | disclosed |
| US-7932331-B2 | Polymerisation of ethylene and α-olefins with imino-quinolinol complexes | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2011-04-26 | — | — | US | disclosed |
| EP-1994006-B1 | POLYMERISATION OF ETHYLENE AND ALPHA-OLEFINS WITH IMINO-QUINOLINOL COMPLEXES | TOTAL PETROCHEMICALS RES FELUY (BE) | 2010-11-17 | — | — | EP | disclosed |
| EP-1994006-B1 | POLYMERISATION OF ETHYLENE AND ALPHA-OLEFINS WITH IMINO-QUINOLINOL COMPLEXES | TOTAL PETROCHEMICALS RES FELUY (BE) | 2010-11-17 | — | — | EP | disclosed |
| US-20100004411-A1 | POLYMERISATION OF ETHYLENE AND ALPHA-OLEFINS WITH IMINO-QUINOLINOL COMPLEXES | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2010-01-07 | — | — | US | disclosed |
| US-20100004411-A1 | POLYMERISATION OF ETHYLENE AND ALPHA-OLEFINS WITH IMINO-QUINOLINOL COMPLEXES | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2010-01-07 | — | — | US | disclosed |
| EP-1994006-A1 | POLYMERISATION OF ETHYLENE AND ALPHA-OLEFINS WITH IMINO-QUINOLINOL COMPLEXES | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2008-11-26 | — | — | EP | disclosed |
| EP-1994006-A1 | POLYMERISATION OF ETHYLENE AND ALPHA-OLEFINS WITH IMINO-QUINOLINOL COMPLEXES | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2008-11-26 | — | — | EP | disclosed |
| WO-2007104680-B1 | POLYMERISATION OF ETHYLENE AND ALPHA-OLEFINS WITH IMINO-QUINOLINOL COMPLEXES | TOTAL PETROCHEMICALS RES FELUY (BE) | 2007-11-22 | — | — | WO | disclosed |
| WO-2007104680-A1 | POLYMERISATION OF ETHYLENE AND ALPHA-OLEFINS WITH IMINO-QUINOLINOL COMPLEXES | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2007-09-20 | — | — | WO | disclosed |
| WO-2007104680-A1 | POLYMERISATION OF ETHYLENE AND ALPHA-OLEFINS WITH IMINO-QUINOLINOL COMPLEXES | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2007-09-20 | — | — | WO | disclosed |
| EP-1832579-A1 | Polymerisation of ethylene and alpha-olefins with imino-quinolinol complexes | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2007-09-12 | — | — | EP | disclosed |
| EP-1832579-A1 | Polymerisation of ethylene and alpha-olefins with imino-quinolinol complexes | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2007-09-12 | — | — | EP | disclosed |
| EP-1832579-A1 | Polymerisation of ethylene and alpha-olefins with imino-quinolinol complexes | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2007-09-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100004411-A1 | POLYMERISATION OF ETHYLENE AND ALPHA-OLEFINS WITH IMINO-QUINOLINOL COMPLEXES | UBE2L3, PCNA, UBE2L6 | NOS3 2289/4885NOS1 2060/4885NOS2 1850/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.