SCHEMBL47849

SCHEMBL47849

CC1=Nc2ccccc2C1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOS3 P29474 1/20 0.43
NOS1 P29475 1/20 0.43
NOS2 P35228 1/20 0.43
HRH4 Q9H3N8 1/20 0.43
TRPA1 O75762 2/20 0.42
SIGMAR1 Q99720 1/20 0.41
NPC1 O15118 5/20 0.41
RAB9A P51151 5/20 0.41
HPGD P15428 1/20 0.41
KMT2A Q03164 5/20 0.39
LMNA P02545 2/20 0.39
PKM P14618 2/20 0.39
TP53 P04637 1/20 0.39
NFKB1 P19838 1/20 0.39
NFKB2 Q00653 1/20 0.39
RELA Q04206 1/20 0.39
ALDH1A1 P00352 4/20 0.37
MAPT P10636 3/20 0.37
ACHE P22303 2/20 0.36
BCHE P06276 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11224074 0.82 KDM4E (0.42) NOS3NOS1NOS2HRH4TRPA1
SCHEMBL30681225 0.79 NOS3 (0.57) NOS3NOS1NOS2HRH4SIGMAR1
SCHEMBL2230501 0.79 NOS3 (0.57) NOS3NOS1NOS2HRH4SIGMAR1
SCHEMBL1105679 0.76 KMT2A (0.38) NPC1RAB9AHPGDKMT2ALMNA
SCHEMBL5021700 0.75 NOS3 (0.46) NOS3NOS1NOS2HRH4TRPA1
SCHEMBL18032671 0.74 TRPA1 (0.45) NOS3NOS1NOS2HRH4TRPA1
SCHEMBL85967 0.74 HRH4 (0.54) NOS3NOS1NOS2HRH4TRPA1
SCHEMBL8177168 0.74 NOS3 (0.42) NOS3NOS1NOS2HRH4TRPA1
SCHEMBL10354061 0.73 KMT2A (0.38) NOS3NOS1NOS2NPC1RAB9A
SCHEMBL10354186 0.73 PDE3B (0.41) NOS3NOS1NOS2NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 550 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0881284-A1 Culture medium for the specific detection of enterobacteries, procedure for its obtention and use Société La Biochimie Appliquée - SO.LA.BI.A. (FR) 1998-12-02 EP claimed
JP-63243952-A None JP disclosed
JP-63180958-A None JP disclosed
JP-63236047-A None JP disclosed
JP-63236049-A None JP disclosed
JP-63236048-A None JP disclosed
JP-63180957-A None JP disclosed
JP-63180959-A None JP disclosed
JP-63180960-A None JP disclosed
JP-1203388-A None JP disclosed
JP-S63180961-A ELECTROPHOTOGRAPHIC SENSITIVE BODY CANON INC 1988-07-26 JP disclosed
JP-S63180959-A ELECTROPHOTOGRAPHIC SENSITIVE BODY CANON INC 1988-07-26 JP disclosed
JP-S6364051-A ELECTROPHOTOGRAPHIC SENSITIVE BODY CANON INC 1988-03-22 JP disclosed
JP-S6364050-A ELECTROPHOTOGRAPHIC SENSITIVE BODY CANON INC 1988-03-22 JP disclosed
JP-S6364052-A ELECTROPHOTOGRAPHIC SENSITIVE BODY CANON INC 1988-03-22 JP disclosed
JP-S6364053-A ELECTROPHOTOGRAPHIC SENSITIVE BODY CANON INC 1988-03-22 JP disclosed
JP-S61177462-A ELECTROPHOTOGRAPHIC SENSITIVE BODY CANON INC 1986-08-09 JP disclosed
US-4419511-A Process for the preparation of trimethine dyestuffs BAYER AKTIENGESELLSCHAFT (US) 1983-12-06 US disclosed
US-3955984-A STYRYL DYES FUJI PHOTO FILM CO., LTD. (JA) 1976-05-11 US disclosed
US-3930851-A ELECTROPHOTOGRAPHIC PROCESS USING METHYLENE INDOLINE PHOTOCONDUCTIVE DERIVATIVES FUJI PHOTO FILM CO., LTD. (JA) 1976-01-06 US disclosed