Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.41 |
| ▸ | HPGD | P15428 | 6/20 | 0.41 |
| ▸ | GAA | P10253 | 5/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 7/20 | 0.39 |
| ▸ | NSD2 | O96028 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | SNCA | P37840 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | MPI | P34949 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9613275 | 0.82 | ATM (0.34) | SMN1; SMN2ACHE | |
| SCHEMBL22856763 | 0.80 | GAA (0.53) | ALDH1A1KDM4EHPGDGAAALOX12 | |
| SCHEMBL24073131 | 0.73 | KDM4E (0.52) | ALDH1A1KDM4EHPGDGAAALOX12 | |
| SCHEMBL17167123 | 0.73 | KDM4E (0.62) | ALDH1A1KDM4EHPGDGAAALOX12 | |
| SCHEMBL9649346 | 0.65 | KDM4E (0.37) | ALDH1A1KDM4EHPGDGAAALOX12 | |
| SCHEMBL9613365 | 0.64 | KDM4E (0.37) | ALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL8746608 | 0.64 | KDM4E (0.42) | ALDH1A1KDM4EHPGDGAAALOX12 | |
| SCHEMBL26209029 | 0.64 | KDM4E (0.53) | ALDH1A1KDM4EHPGDGAAALOX12 | |
| SCHEMBL12114738 | 0.62 | GAA (0.34) | ALDH1A1KDM4EHPGDGAAMAPT | |
| SCHEMBL22510027 | 0.62 | ALDH1A1 (0.36) | ALDH1A1KDM4EHPGDGAAALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8053039-B2 | Polymerizable dichroic azo dyes | ROLIC AG (CH) | 2011-11-08 | — | — | US | disclosed |