Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | HPGD | P15428 | 5/20 | 0.52 |
| ▸ | NSD2 | O96028 | 5/20 | 0.52 |
| ▸ | GAA | P10253 | 4/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | APP | P05067 | 1/20 | 0.52 |
| ▸ | SNCA | P37840 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MPI | P34949 | 2/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.43 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17167123 | 0.88 | KDM4E (0.62) | KDM4EALDH1A1MAPTHPGDNSD2 | |
| SCHEMBL16350339 | 0.73 | ALDH1A1 (0.41) | KDM4EALDH1A1MAPTHPGDNSD2 | |
| SCHEMBL24074561 | 0.72 | ALDH1A1 (0.76) | KDM4EALDH1A1MAPTHPGDNSD2 | |
| SCHEMBL17312214 | 0.69 | KDM4E (0.44) | KDM4EALDH1A1MAPTHPGDNSD2 | |
| SCHEMBL17847287 | 0.69 | KDM4E (0.44) | KDM4EALDH1A1MAPTHPGDNSD2 | |
| SCHEMBL9155726 | 0.68 | KDM4E (1.00) | KDM4EALDH1A1MAPTHPGDNSD2 | |
| SCHEMBL19846480 | 0.68 | KDM4E (0.61) | KDM4EALDH1A1MAPTHPGDNSD2 | |
| SCHEMBL24074836 | 0.68 | ALDH1A1 (0.62) | KDM4EALDH1A1MAPTHPGDNSD2 | |
| SCHEMBL9334456 | 0.67 | ALDH1A1 (0.52) | KDM4EALDH1A1MAPTHPGDNSD2 | |
| SCHEMBL24074586 | 0.63 | ALDH1A1 (0.50) | KDM4EALDH1A1MAPTHPGDNSD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021239191-A1 | PERIMIDINE DERIVATIVES AND USE THEREOF | TECHNISCHE UNIVERSITÄT BERGAKADEMIE FREIBERG (DE) | 2021-12-02 | — | — | WO | disclosed |