Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.42 |
| ▸ | GRB2 | P62993 | 1/20 | 0.42 |
| ▸ | APLNR | P35414 | 1/20 | 0.41 |
| ▸ | CAPN1 | P07384 | 6/20 | 0.40 |
| ▸ | NTSR2 | O95665 | 2/20 | 0.40 |
| ▸ | NTSR1 | P30989 | 2/20 | 0.40 |
| ▸ | PLG | P00747 | 3/20 | 0.40 |
| ▸ | PLAT | P00750 | 2/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16351033 | 0.92 | APLNR (0.48) | GRB2APLNRCAPN1NTSR2NTSR1 | |
| SCHEMBL16351239 | 0.92 | APLNR (0.48) | GRB2APLNRCAPN1NTSR2NTSR1 | |
| SCHEMBL16330330 | 0.92 | APLNR (0.48) | GRB2APLNRCAPN1NTSR2NTSR1 | |
| SCHEMBL16350326 | 0.89 | OPRM1 (0.43) | F2GRB2APLNRCAPN1PLG | |
| SCHEMBL29530904 | 0.80 | XIAP (0.48) | F2GRB2CAPN1NTSR2NTSR1 | |
| SCHEMBL10783008 | 0.80 | ACE (0.53) | — | |
| SCHEMBL8760024 | 0.80 | ACE (0.53) | — | |
| SCHEMBL10782979 | 0.80 | ACE (0.53) | — | |
| SCHEMBL8760014 | 0.80 | ACE (0.53) | — | |
| SCHEMBL1246765 | 0.80 | DPP4 (0.42) | GRB2CAPN1NTSR2NTSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8263739-B2 | also targeting tumor cells that express vascular endothelial growth factor neuropilin-1 receptor; radiotherapy; radiopharmaceuticals; treating angiogenesis | BRACCO SUISSE SA (CH) | 2012-09-11 | — | — | US | disclosed |