Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.71 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.68 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.68 |
| ▸ | ESR1 | P03372 | 3/20 | 0.63 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.63 |
| ▸ | CA1 | P00915 | 1/20 | 0.61 |
| ▸ | CA2 | P00918 | 1/20 | 0.61 |
| ▸ | CA9 | Q16790 | 1/20 | 0.61 |
| ▸ | ERN1 | O75460 | 3/20 | 0.51 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.48 |
| ▸ | NQO1 | P15559 | 1/20 | 0.47 |
| ▸ | NQO2 | P16083 | 1/20 | 0.47 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.47 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.45 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.45 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29766071 | 1.00 | APP (0.71) | APPHSD17B1HSD17B2ESR1ESR2 | |
| Bromide SCHEMBL31564934 | 0.98 | APP (0.69) | APPHSD17B1HSD17B2ESR1ESR2 | |
| SCHEMBL5768436 | 0.96 | APP (0.72) | APPHSD17B1HSD17B2ESR1ESR2 | |
| Formaldehyde SCHEMBL27872210 | 0.94 | APP (0.65) | APPHSD17B1HSD17B2ESR1ESR2 | |
| SCHEMBL27631114 | 0.93 | HSD17B1 (0.77) | APPHSD17B1HSD17B2ESR1ESR2 | |
| SCHEMBL32677328 | 0.93 | APP (0.81) | APPHSD17B1HSD17B2ESR1ESR2 | |
| SCHEMBL27159530 | 0.93 | APP (0.81) | APPHSD17B1HSD17B2ESR1ESR2 | |
| SCHEMBL30340807 | 0.92 | HSD17B1 (0.75) | APPHSD17B1HSD17B2ESR1ESR2 | |
| Trimethylammonium SCHEMBL11529523 | 0.92 | APP (0.62) | APPHSD17B1HSD17B2ESR1ESR2 | |
| SCHEMBL21476763 | 0.89 | APP (0.69) | APPHSD17B1HSD17B2ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 355 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119143678-A | Fluorescent molecule for rapidly measuring excitation light spot size and light intensity distribution and preparation method thereof | 中国科学院化学研究所 | 2024-12-17 | — | — | CN | claimed |
| US-11932657-B2 | Heterocyclic compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2024-03-19 | — | — | US | claimed |
| CN-117202752-A | Imaging element, stacked imaging element, imaging device, and electronic device | 索尼公司 | 2023-12-08 | — | — | CN | claimed |
| CN-117202754-A | Imaging element, stacked imaging element, imaging device, and electronic device | 索尼公司 | 2023-12-08 | — | — | CN | claimed |
| CN-117202753-A | Imaging element, stacked imaging element, imaging device, and electronic device | 索尼公司 | 2023-12-08 | — | — | CN | claimed |
| CN-109952652-B | Imaging element, stacked imaging element, imaging device, and electronic device | 索尼公司 | 2023-09-19 | — | — | CN | claimed |
| CN-115073420-A | Preparation method of 2-phenylbenzothiophene derivative | 陕西维世诺新材料有限公司 | 2022-09-20 | — | — | CN | claimed |
| CN-111253366-B | Phenyl benzothiophene rod-shaped liquid crystal compound and preparation method thereof | 四川师范大学 | 2022-06-17 | — | — | CN | claimed |
| CN-114447243-A | Organic electroluminescent device comprising light-emitting layer and hole transport region | 吉林奥来德光电材料股份有限公司 | 2022-05-06 | — | — | CN | claimed |
| CN-113678273-A | Photoelectric conversion element and imaging device | 索尼集团公司 | 2021-11-19 | — | — | CN | claimed |
| CN-104974227-B | The amphiphilic film targeting alpha-helix polypeptide of cation and its application | 中国科学院苏州纳米技术与纳米仿生研究所 | 2019-04-23 | — | — | CN | claimed |
| CN-107129519-A | Polypeptide fluorescence cyclization method and cyclized polypeptide based on metal iridium complex | 中国科学院苏州纳米技术与纳米仿生研究所 | 2017-09-05 | — | — | CN | claimed |
| CN-101750486-A | Method for labeling antibody by fluorophore generated by combination of iridium coordination compound and histidine | SUNA TECH INC | 2010-06-23 | — | — | CN | claimed |
| US-20070099876-A1 | Target directed chemotherapy of tumours of the sexual organs | TRIN GMBH (CH) | 2007-05-03 | — | — | US | claimed |
| EP-1636249-A1 | TARGET-ORIENTED CHEMOTHERAPY FOR TREATING TUMORS OF THE SEXUAL ORGANS | TRIN GmbH (CH) | 2006-03-22 | — | — | EP | claimed |
| WO-2004106358-A1 | TARGET-ORIENTED CHEMOTHERAPY FOR TREATING TUMORS OF THE SEXUAL ORGANS | TRIN GMBH (CH) | 2004-12-09 | — | — | WO | claimed |
| US-6395769-B1 | ACTIVATION ESTROGEN; THERAPY FOR OSTEOPOROSIS, ANTILIPEMIC AGENTS | ELI LILLY AND COMPANY | 2002-05-28 | — | — | US | claimed |
| US-6096781-A | 2-PHENYL-1-BENZOTHIOPHENE DERIVATIVES ARE USEFUL FOR TREATMENT OF OSTEOPOROSIS AND HYPERLIPEMIA | ELI LILLY AND COMPANY (US) | 2000-08-01 | — | — | US | claimed |
| EP-0920862-A1 | 2-Arylbenzo b thiophenes useful for the treatment of estrogen deprivation syndrome | ELI LILLY AND COMPANY (US) | 1999-06-09 | — | — | EP | claimed |
| US-4092161-A | Inorganic photoconductors with phenyl substituted image transport materials | XEROX CORPORATION (US) | 1978-05-30 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070099876-A1 | Target directed chemotherapy of tumours of the sexual organs | GPER1, SHBG, GNRHR | APP 4881/4885HSD17B1 81/4885HSD17B2 55/4885 |
| US-11932657-B2 | Heterocyclic compound | AHR, PDGFRA, PDGFRB | APP 2636/4885HSD17B1 545/4885HSD17B2 539/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.