Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.42 |
| ▸ | RBP4 | P02753 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16354254 | 0.87 | TSHR (0.47) | HPGDMEN1KMT2ACYP3A4CYP2C9 | |
| SCHEMBL700427 | 0.79 | LMNA (0.53) | LMNAPOLBHPGDMEN1KMT2A | |
| SCHEMBL9370064 | 0.78 | LMNA (0.62) | LMNAPOLBHPGDMEN1KMT2A | |
| SCHEMBL16354340 | 0.75 | CYP11B1 (0.52) | LMNAPOLBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL15703769 | 0.75 | ALDH1A1 (0.48) | LMNA | |
| SCHEMBL30788253 | 0.70 | ALDH1A1 (0.67) | LMNAPOLBMEN1KMT2AGAA | |
| SCHEMBL27179827 | 0.70 | ALDH1A1 (0.67) | LMNAPOLBMEN1KMT2AGAA | |
| SCHEMBL11480218 | 0.69 | HPGD (1.00) | LMNAPOLBHPGDMEN1KMT2A | |
| SCHEMBL16354335 | 0.69 | POLB (0.55) | LMNAPOLBMEN1KMT2ATSHR | |
| SCHEMBL16354304 | 0.68 | CYP11B1 (0.49) | MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2421823-B1 | AZETIDINYL DIAMIDES AS MONOACYLGLYCEROL LIPASE INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2015-01-14 | — | — | EP | claimed |