SCHEMBL1635519

SCHEMBL1635519

O=C(O)N1C(=O)CC(O)C1=O

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14391569 0.80 NOTUM (0.35) MAPT
SCHEMBL8815627 0.79
SCHEMBL3944013 0.75
SCHEMBL7157486 0.75 GSK3B (0.43)
Bicarbonate SCHEMBL9560498 0.73 MAPT (0.31) MAPT
Oxalic Acid SCHEMBL9221351 0.71 ACE (0.31)
SCHEMBL4407911 0.71
SCHEMBL9708934 0.69
SCHEMBL5919521 0.68 TSHR (0.49)
Succinic Acid SCHEMBL6865697 0.67 LMNA (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040023048-A1 Enhanced bonding layers on native oxide surfaces NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2004-02-05 US claimed
US-8993117-B2 Devices with multiple surface functionality THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2015-03-31 US disclosed
US-20120121661-A1 DEVICES WITH MULTIPLE SURFACE FUNCTIONALITY THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2012-05-17 US disclosed
US-20120114935-A1 DEVICES WITH MULTIPLE SURFACE FUNCTIONALITY THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2012-05-10 US disclosed
US-7931943-B2 Depositing a layer of an omega functionalized organophosphorous compound on an oxide substrate, heating, depositing another layer by heating and bonding through the omega functionalized group; implantable medical devices THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2011-04-26 US disclosed
US-7507483-B2 Enhanced bonding layers on native oxide surfaces NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2009-03-24 US disclosed
US-20080166470-A1 Enhanced Bonding Layers on Native Oxide Surfaces THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2008-07-10 US disclosed
US-20060194008-A1 Devices with multiple surface functionality PRINCETON UNIVERSITY (US) 2006-08-31 US disclosed
US-20040023048-A1 Enhanced bonding layers on native oxide surfaces NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2004-02-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120121661-A1 DEVICES WITH MULTIPLE SURFACE FUNCTIONALITY PHOSPHO1, CD44, SELP MAPT 4354/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.