Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC34A2 | O95436 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | HPGD | P15428 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CFD | P00746 | 2/20 | 0.35 |
| ▸ | BDKRB1 | P46663 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.34 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16804647 | 1.00 | SLC34A2 (0.48) | SLC34A2KDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL18471348 | 0.99 | SLC34A2 (0.49) | SLC34A2KDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL15432815 | 0.91 | SLC34A2 (0.46) | SLC34A2KDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL16355234 | 0.89 | BDKRB1 (0.39) | SLC34A2LMNACFDBDKRB1DHODH | |
| SCHEMBL19596363 | 0.89 | BDKRB1 (0.39) | SLC34A2LMNACFDBDKRB1DHODH | |
| SCHEMBL6000159 | 0.89 | CFD (0.40) | SLC34A2KDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL15432811 | 0.89 | BDKRB1 (0.38) | SLC34A2LMNACFDBDKRB1DHODH | |
| SCHEMBL16804646 | 0.89 | BDKRB1 (0.38) | SLC34A2LMNACFDBDKRB1DHODH | |
| SCHEMBL18482341 | 0.88 | SLC34A2 (0.41) | SLC34A2KDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL47757 | 0.85 | SLC34A2 (0.54) | SLC34A2KDM4EALDH1A1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8916569-B2 | Compounds and methods for inhibiting phosphate transport | ARDELYX, INC. (US) | 2014-12-23 | — | — | US | disclosed |