SCHEMBL16356283

SCHEMBL16356283

CCCCN1C(=O)c2c(Br)sc(Br)c2C1=O

nearest known ligand 0.39

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.39
MAPT P10636 2/20 0.39
PTGS2 P35354 4/20 0.37
PTGS1 P23219 3/20 0.37
MGLL Q99685 2/20 0.37
FAAH O00519 1/20 0.37
CNR1 P21554 2/20 0.36
RGS4 P49798 3/20 0.35
RGS8 P57771 2/20 0.35
SMN1; SMN2 Q16637 3/20 0.35
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
ATM Q13315 1/20 0.33
GSK3B P49841 1/20 0.33
ALDH2 P05091 1/20 0.33
ALDH3A1 P30838 1/20 0.33
TP53 P04637 1/20 0.33
GAA P10253 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15979461 0.93 MGLL (0.47) ALDH1A1PTGS2PTGS1MGLLFAAH
SCHEMBL2053670 0.93 MGLL (0.47) ALDH1A1PTGS2PTGS1MGLLFAAH
SCHEMBL1041919 0.93 MGLL (0.47) ALDH1A1PTGS2PTGS1MGLLFAAH
SCHEMBL16594677 0.93 MGLL (0.47) ALDH1A1PTGS2PTGS1MGLLFAAH
SCHEMBL13096354 0.93 MGLL (0.47) ALDH1A1PTGS2PTGS1MGLLFAAH
SCHEMBL15979460 0.93 MGLL (0.47) ALDH1A1PTGS2PTGS1MGLLFAAH
SCHEMBL15422601 0.84 MGLL (0.43) ALDH1A1PTGS2PTGS1MGLLFAAH
SCHEMBL17412781 0.84 PTGS1 (0.40) ALDH1A1PTGS2PTGS1MGLLFAAH
SCHEMBL16356281 0.81 ALDH1A1 (0.33) ALDH1A1MAPTSMN1; SMN2NPC1RAB9A
SCHEMBL3683409 0.80 CA12 (0.41) ALDH1A1MAPTPTGS2PTGS1MGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2927259-B1 BENZODITHIOPHENE BASED COPOLYMER CONTAINING THIOPHENE PYRROLEDIONE UNITS AND PREPARING METHOD AND APPLICATIONS THEREOF OCEANS KING LIGHTING SCIENCE&TECHNOLOGY CO LTD (CN) 2018-08-01 EP disclosed
US-9412950-B2 Polymer compound and organic photoelectric conversion device SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-08-09 US disclosed
US-9412950-B2 Polymer compound and organic photoelectric conversion device SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-08-09 US disclosed
US-9328204-B2 Benzodithiophene based copolymer containing thiophene pyrroledione units and preparing method and applications thereof OCEAN'S KING LIGHTING SCIENCE & TECHNOLOGY CO., LTD. (CN) 2016-05-03 US disclosed
US-9328204-B2 Benzodithiophene based copolymer containing thiophene pyrroledione units and preparing method and applications thereof OCEAN'S KING LIGHTING SCIENCE & TECHNOLOGY CO., LTD. (CN) 2016-05-03 US disclosed
US-20150307663-A1 BENZODITHIOPHENE BASED COPOLYMER CONTAINING THIOPHENE PYRROLEDIONE UNITS AND PREPARING METHOD AND APPLICATIONS THEREOF OCEAN'S KING LIGHTING SCIENCE & TECHNOLOGY CO., LTD. (CN) 2015-10-29 US disclosed
US-20150307663-A1 BENZODITHIOPHENE BASED COPOLYMER CONTAINING THIOPHENE PYRROLEDIONE UNITS AND PREPARING METHOD AND APPLICATIONS THEREOF OCEAN'S KING LIGHTING SCIENCE & TECHNOLOGY CO., LTD. (CN) 2015-10-29 US disclosed
EP-2927259-A1 BENZODITHIOPHENE BASED COPOLYMER CONTAINING THIOPHENE PYRROLEDIONE UNITS AND PREPARING METHOD AND APPLICATIONS THEREOF Ocean's King Lighting Science&Technology Co., Ltd. (CN) 2015-10-07 EP disclosed
US-20140373912-A1 POLYMER COMPOUND AND ORGANIC PHOTOELECTRIC CONVERSION DEVICE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-12-25 US disclosed
US-20140373912-A1 POLYMER COMPOUND AND ORGANIC PHOTOELECTRIC CONVERSION DEVICE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-12-25 US disclosed