Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.53 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CTSL | P07711 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | CTSK | P43235 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3838580 | 0.90 | PARP1 (0.63) | PARP1ATMTDP1L3MBTL1CTSL | |
| SCHEMBL9353591 | 0.87 | CES2 (0.59) | PARP1ATMTDP1L3MBTL1CTSL | |
| SCHEMBL3838117 | 0.86 | PARP1 (0.59) | PARP1ATMTDP1L3MBTL1CTSL | |
| SCHEMBL209624 | 0.86 | ATM (0.67) | ATMTDP1L3MBTL1CTSLMEN1 | |
| SCHEMBL241785 | 0.86 | PARP1 (0.68) | PARP1ATMTDP1L3MBTL1CTSL | |
| SCHEMBL30153175 | 0.86 | PARP1 (0.68) | PARP1ATMTDP1L3MBTL1CTSL | |
| SCHEMBL9125529 | 0.85 | CES2 (0.59) | PARP1HSD11B1ATML3MBTL1CTSL | |
| SCHEMBL2013121 | 0.85 | PARP1 (0.53) | PARP1HSD11B1ATMTDP1L3MBTL1 | |
| SCHEMBL40538 | 0.84 | ATM (0.71) | PARP1ATMTDP1L3MBTL1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL27869733 | 0.84 | PARP1 (0.65) | PARP1ATMTDP1L3MBTL1CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6303733-B1 | FROM BISPHENOL COMPOUNDS AND DIFLUORO DIARYLACETYLENES AND/OR ETHYNYLATED BENZOPHENONES; DIELECTRICS EMPLOYED WITH A VARIETY OF MICROELECTRONIC DEVICES, FOR EXAMPLE, INTEGRATED CIRCUITS AND MULTICHIP MODULES. | ALLIEDSIGNAL INC. | 2001-10-16 | — | — | US | claimed |
| WO-2000031163-A2 | POLY(ARYLENE ETHER) HOMOPOLYMER COMPOSITIONS AND METHODS OF MANUFACTURE THEREOF | ALLIEDSIGNAL INC. (US) | 2000-06-02 | — | — | WO | claimed |
| US-9914724-B2 | C-aryl glycosid derivatives, pharmaceutical composition, preparation process and uses thereof | Shanghai De Novo Pharmatech Co., Ltd. (CN) | 2018-03-13 | — | — | US | disclosed |
| US-9914724-B2 | C-aryl glycosid derivatives, pharmaceutical composition, preparation process and uses thereof | Shanghai De Novo Pharmatech Co., Ltd. (CN) | 2018-03-13 | — | — | US | disclosed |
| US-9914724-B2 | C-aryl glycosid derivatives, pharmaceutical composition, preparation process and uses thereof | Shanghai De Novo Pharmatech Co., Ltd. (CN) | 2018-03-13 | — | — | US | disclosed |
| EP-3133071-A1 | C-ARYL INDICAN DERIVATIVE, AND PHARMACEUTICAL COMPOSITION THEREOF, PREPARATION METHOD THEREFOR AND USES THEREOF | Shanghai De Novo Pharmatech Co Ltd. (CN) | 2017-02-22 | — | — | EP | disclosed |
| EP-3133071-A1 | C-ARYL INDICAN DERIVATIVE, AND PHARMACEUTICAL COMPOSITION THEREOF, PREPARATION METHOD THEREFOR AND USES THEREOF | Shanghai De Novo Pharmatech Co Ltd. (CN) | 2017-02-22 | — | — | EP | disclosed |
| US-20170037038-A1 | C- ARYL GLYCOSID DERIVATIVES, PHARMACEUTICAL COMPOSITION, PREPARATION PROCESS AND USES THEREOF | SHANGHAI DE NOVO PHARMATECH CO. LTD. (CN) | 2017-02-09 | — | — | US | disclosed |
| US-20170037038-A1 | C- ARYL GLYCOSID DERIVATIVES, PHARMACEUTICAL COMPOSITION, PREPARATION PROCESS AND USES THEREOF | SHANGHAI DE NOVO PHARMATECH CO. LTD. (CN) | 2017-02-09 | — | — | US | disclosed |
| US-20170037038-A1 | C- ARYL GLYCOSID DERIVATIVES, PHARMACEUTICAL COMPOSITION, PREPARATION PROCESS AND USES THEREOF | SHANGHAI DE NOVO PHARMATECH CO. LTD. (CN) | 2017-02-09 | — | — | US | disclosed |
| WO-2015158206-A1 | C-ARYL INDICAN DERIVATIVE, AND PHARMACEUTICAL COMPOSITION THEREOF, PREPARATION METHOD THEREFOR AND USES THEREOF | 上海迪诺医药科技有限公司 | 2015-10-22 | — | — | WO | disclosed |
| EP-1171516-A1 | POLYMERS HAVING BACKBONES WITH REACTIVE GROUPS EMPLOYED IN CROSSLINKING AS PRECURSORS TO NANOPOROUS THIN FILM STRUCTURES | AlliedSignal Inc. (US) | 2002-01-16 | — | — | EP | disclosed |
| US-6313185-B1 | PROVIDING POLYMERIC STRANDS WHEREIN EACH OF THE POLYMERIC STRANDS INCLUDES THERMOLABILE PORTION, AND DEFINES A BACKBONE INCLUDING REACTIVE GROUPS; PROVIDING ENERGY TO CROSSLINK; PROVIDING ENERGY TO PARTIALLY DERGADE THERMOLABILE PORTION | HONEYWELL INTERNATIONAL INC. | 2001-11-06 | — | — | US | disclosed |
| US-6303733-B1 | FROM BISPHENOL COMPOUNDS AND DIFLUORO DIARYLACETYLENES AND/OR ETHYNYLATED BENZOPHENONES; DIELECTRICS EMPLOYED WITH A VARIETY OF MICROELECTRONIC DEVICES, FOR EXAMPLE, INTEGRATED CIRCUITS AND MULTICHIP MODULES. | ALLIEDSIGNAL INC. | 2001-10-16 | — | — | US | disclosed |
| WO-2000061667-A1 | POLYMERS HAVING BACKBONES WITH REACTIVE GROUPS EMPLOYED IN CROSSLINKING AS PRECURSORS TO NANOPOROUS THIN FILM STRUCTURES | ALLIEDSIGNAL INC. (US) | 2000-10-19 | — | — | WO | disclosed |
| US-6124421-A | A SEMICONDUCTOR DEVICE COMPRISING A DIELECTRIC LAYER DISPOSED OVERLYING A SURFACE, COMPRISES A POLY(ARYLENE ETHER) | ALLIEDSIGNAL INC. (US) | 2000-09-26 | — | — | US | disclosed |
| WO-2000031163-A2 | POLY(ARYLENE ETHER) HOMOPOLYMER COMPOSITIONS AND METHODS OF MANUFACTURE THEREOF | ALLIEDSIGNAL INC. (US) | 2000-06-02 | — | — | WO | disclosed |
| EP-0425930-B1 | Process for the preparation of symmetrical diarylacetylenes | BAYER AG (DE) | 1994-09-28 | — | — | EP | disclosed |
| US-5185454-A | Reacting aryl bromide with acetylene in presence of palladium catalyst and nitrogen-containing heterocyclic base | BAYER AKTIENGESELLSCHAFT (DE) | 1993-02-09 | — | — | US | disclosed |
| EP-0425930-A2 | Process for the preparation of symmetrical diarylacetylenes | BAYER AG (DE) | 1991-05-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170037038-A1 | C- ARYL GLYCOSID DERIVATIVES, PHARMACEUTICAL COMPOSITION, PREPARATION PROCESS AND USES THEREOF | SLC5A2, SLC5A1, MGAT1 | PARP1 2600/4885HSD11B1 361/4885ATM 3896/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.