SCHEMBL241785

SCHEMBL241785

O=C(c1cccc(Br)c1)c1cccc(Br)c1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 1/20 0.68
ALDH1A1 P00352 1/20 0.59
TP53 P04637 1/20 0.59
L3MBTL1 Q9Y468 3/20 0.58
TDP1 Q9NUW8 2/20 0.58
ATM Q13315 1/20 0.58
C1S P09871 1/20 0.56
HPGD P15428 2/20 0.55
MEN1 O00255 2/20 0.53
GAA P10253 2/20 0.53
KMT2A Q03164 2/20 0.53
MAPT P10636 1/20 0.53
MAOA P21397 1/20 0.53
MAOB P27338 1/20 0.53
ALOX15 P16050 1/20 0.52
HTT P42858 1/20 0.52
SMN1; SMN2 Q16637 3/20 0.52
CTSL P07711 1/20 0.51
NPC1 O15118 2/20 0.50
RAB9A P51151 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30153175 1.00 PARP1 (0.68) PARP1ALDH1A1TP53L3MBTL1TDP1
Hydrochloric Acid SCHEMBL27869733 0.98 PARP1 (0.65) PARP1ALDH1A1TP53L3MBTL1TDP1
SCHEMBL3838580 0.95 PARP1 (0.63) PARP1ALDH1A1TP53L3MBTL1TDP1
SCHEMBL40538 0.93 ATM (0.71) PARP1ALDH1A1TP53L3MBTL1TDP1
SCHEMBL3838117 0.91 PARP1 (0.59) PARP1ALDH1A1TP53L3MBTL1TDP1
SCHEMBL30136033 0.89 FASN (0.61) PARP1ALDH1A1TP53TDP1MEN1
SCHEMBL18529814 0.89 FASN (0.61) PARP1ALDH1A1TP53TDP1MEN1
SCHEMBL18529829 0.88 CTSL (0.58) PARP1ALDH1A1TP53L3MBTL1TDP1
SCHEMBL1668717 0.88 ALDH1A1 (0.59) PARP1ALDH1A1TP53L3MBTL1TDP1
SCHEMBL9353671 0.88 PARP1 (0.55) PARP1ALDH1A1TP53L3MBTL1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 181 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108947924-A The preparation method and its usage of dihydro-isoxazole methanone derivatives and dihydro-isoxazole methanone derivatives 石河子大学 2018-12-07 CN claimed
CN-104080783-A Pyrrole compounds YAKULT HONSHA KK 2014-10-01 CN claimed
CN-104016898-A 3,4-disubstituted pyrrole compound as well as preparation method and application thereof UNIV SHANGHAI JIAOTONG 2014-09-03 CN claimed
CN-100343256-C Biaryl substituted diazabicycloalkane amides as nicotinic acetylcholine agonists ASTRAZENECA AB (SE) 2007-10-17 CN claimed
CN-1678615-A Biaryl substituted diazabicycloalkanes as nicotinic acetylcholine antagonists ASTRAZENECA AB (SE) 2005-10-05 CN claimed
US-20250115628-A1 FLUORINATED FLUOROPHORES HOWARD HUGHES MEDICAL INSTITUTE 2025-04-10 US disclosed
CN-119409717-A Boron-containing compound and application thereof 北京燕化集联光电技术有限公司 2025-02-11 CN disclosed
WO-2024117245-A1 POLYARYL ETHER KETONE RESIN COMPOSITION, MOLDED ARTICLE OF SAME AND METHOD FOR PRODUCING POLYARYL ETHER KETONE RESIN COMPOSITION 本州化学工業株式会社 2024-06-06 WO disclosed
WO-2023202471-A1 TETRADENTATE PLATINUM COMPLEX LIGHT-EMITTING MATERIAL CONTAINING SPIRO STRUCTURE AND USE THEREOF 广东阿格蕾雅光电材料有限公司 2023-10-26 WO disclosed
US-20230285378-A1 Anti-Viral Compounds ABBVIE INC. (US) 2023-09-14 US disclosed
US-20230285378-A1 Anti-Viral Compounds ABBVIE INC. (US) 2023-09-14 US disclosed
US-20230285378-A1 Anti-Viral Compounds ABBVIE INC. (US) 2023-09-14 US disclosed
EP-0415678-A2 Poly(phenylene sulfide ketone) ferromagnetic substance Tosoh Corporation (JP) 1991-03-06 EP disclosed
US-4963651-A VAPOR PHASE SEPARATION; COOLING, SOLIDIFYING, SLURRYING PHILLIPS PETROLEUM COMPANY (US) 1990-10-16 US disclosed
EP-0346085-A2 Process for producing polyphenylene sulfide ketone polymers Tosoh Corporation (JP) 1989-12-13 EP disclosed
US-4612400-A Autoxidation of bis(ortho dialkyl-phenoxy)benzophenones THE DOW CHEMICAL COMPANY (US) 1986-09-16 US disclosed
US-4577034-A Autoxidation of bis(ortho dialkyl-phenoxy)benzophenones THE DOW CHEMICAL COMPANY (US) 1986-03-18 US disclosed
US-4175945-A PLANT GROWTH REGULATORS FOR TABACCO ROHM AND HAAS COMPANY (US) 1979-11-27 US disclosed
US-4120687-A CONTROLLING GROWTH OF TOBACCO SUCKERS MEISINGER ROBERT H 1978-10-17 US disclosed
US-4017313-A Photosensitive composition containing a leuco dye, a photosensitizer, an aromatic aldehyde and a secondary or tertiary amine and the use thereof in a direct-print process E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-04-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230285378-A1 Anti-Viral Compounds HAVCR2, EIF2AK2, MAVS PARP1 2308/4885ALDH1A1 2858/4885TP53 996/4885
US-20250115628-A1 FLUORINATED FLUOROPHORES PFAS, FLI1, ARFGEF1 PARP1 652/4885ALDH1A1 1109/4885TP53 181/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.