Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | USP2 | O75604 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | LIPE | Q05469 | 1/20 | 0.50 |
| ▸ | CCR1 | P32246 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9891789 | 0.85 | MAPK1 (0.62) | MAPK1POLBALDH1A1USP2TSHR | |
| SCHEMBL11833579 | 0.82 | MAPK1 (0.59) | MAPK1POLBALDH1A1USP2TSHR | |
| SCHEMBL16356402 | 0.81 | MAPK1 (0.55) | MAPK1POLBALDH1A1USP2TSHR | |
| Hydrochloric Acid SCHEMBL6913635 | 0.81 | MAPK1 (0.57) | MAPK1POLBALDH1A1USP2TSHR | |
| Hydrochloric Acid SCHEMBL7632441 | 0.81 | MAPK1 (0.57) | MAPK1POLBALDH1A1USP2TSHR | |
| SCHEMBL16435180 | 0.79 | NAMPT (0.64) | MAPK1POLBALDH1A1USP2TSHR | |
| SCHEMBL14037733 | 0.79 | NAMPT (0.64) | MAPK1POLBALDH1A1USP2TSHR | |
| SCHEMBL31256906 | 0.78 | MAPK1 (0.55) | MAPK1POLBALDH1A1USP2TSHR | |
| Piperazine SCHEMBL28323312 | 0.78 | MAPK1 (0.55) | MAPK1POLBALDH1A1USP2TSHR | |
| SCHEMBL6911754 | 0.78 | POLB (0.58) | MAPK1POLBALDH1A1USP2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007064749-A1 | COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS AND MICROBIAL DISEASES | SCHERING CORPORATION (US) | 2007-06-07 | — | — | WO | disclosed |