Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | USP2 | O75604 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16357643 | 0.81 | MAPK1 (0.57) | MAPK1ALDH1A1MEN1KMT2AUSP2 | |
| SCHEMBL10898288 | 0.76 | MAPK1 (0.62) | MAPK1ALDH1A1MEN1KMT2AUSP2 | |
| SCHEMBL9891789 | 0.76 | MAPK1 (0.62) | MAPK1ALDH1A1MEN1KMT2AUSP2 | |
| SCHEMBL27623186 | 0.74 | MAPK1 (0.56) | MAPK1ALDH1A1MEN1KMT2AUSP2 | |
| SCHEMBL11833579 | 0.73 | MAPK1 (0.59) | MAPK1ALDH1A1MEN1KMT2AUSP2 | |
| SCHEMBL631962 | 0.73 | ALDH1A1 (0.69) | MAPK1ALDH1A1MEN1KMT2AUSP2 | |
| SCHEMBL27792690 | 0.73 | AKR1C3 (0.82) | MAPK1ALDH1A1MEN1KMT2AUSP2 | |
| SCHEMBL16357732 | 0.73 | MMP1 (0.37) | ALDH1A1HTT | |
| Hydrochloric Acid SCHEMBL7632441 | 0.72 | MAPK1 (0.57) | MAPK1ALDH1A1MEN1KMT2AUSP2 | |
| Hydrochloric Acid SCHEMBL6913635 | 0.72 | MAPK1 (0.57) | MAPK1ALDH1A1MEN1KMT2AUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007064749-A1 | COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS AND MICROBIAL DISEASES | SCHERING CORPORATION (US) | 2007-06-07 | — | — | WO | disclosed |