SCHEMBL163580

SCHEMBL163580

O=C1CCCCc2ccccc21

nearest known ligand 0.91

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 7/20 0.91
MAOB P27338 6/20 0.91
CYP2A6 P11509 1/20 0.91
CES1 P23141 2/20 0.56
TSHR P16473 1/20 0.55
HPGD P15428 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
GRM5 P41594 1/20 0.49
PRKCI P41743 1/20 0.48
PDPK1 O15530 1/20 0.47
PARP1 P09874 1/20 0.47
PARP10 Q53GL7 1/20 0.47
PARP11 Q9NR21 1/20 0.47
BCHE P06276 1/20 0.46
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
MAPT P10636 1/20 0.46
MIF P14174 1/20 0.46
NOS3 P29474 1/20 0.44
HSD17B1 P14061 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29766301 1.00 MAOA (0.91) MAOAMAOBCYP2A6CES1TSHR
SCHEMBL4874556 1.00 MAOA (0.91) MAOAMAOBCYP2A6CES1TSHR
SCHEMBL18607288 1.00 MAOA (0.91) MAOAMAOBCYP2A6CES1TSHR
SCHEMBL4573854 1.00 MAOA (0.91) MAOAMAOBCYP2A6CES1TSHR
SCHEMBL20445627 1.00 MAOA (0.91) MAOAMAOBCYP2A6CES1TSHR
SCHEMBL18716863 1.00 MAOA (0.91) MAOAMAOBCYP2A6CES1TSHR
Ammonia Solution, Strong SCHEMBL28684723 0.98 MAOA (0.87) MAOAMAOBCYP2A6CES1TSHR
SCHEMBL10456794 0.96 MAOA (0.91) MAOAMAOBCYP2A6CES1TSHR
SCHEMBL44545 0.95 MAOA (1.00) MAOAMAOBCYP2A6CES1TSHR
SCHEMBL29351871 0.95 MAOA (1.00) MAOAMAOBCYP2A6CES1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 889 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120192265-A Benzocycloheptanonocarbazole derivative and preparation method and application thereof 西安欧得光电材料有限公司 2025-06-24 CN claimed
CN-119306681-A Synthesis method of 3-oxazoline-5-ketone and derivative thereof 湖南医药学院 2025-01-14 CN claimed
CN-113620795-B Method for synthesizing benzocycloheptenone compounds 河南师范大学 2022-07-01 CN claimed
EP-3847157-B1 PROCESS FOR THE PREPARATION OF METHYL 6-(2,4-DICHLOROPHENYL)-5-[4-[(3S)-1-(3-FLUOROPROPYL)PYRROLIDIN-3-YL]OXYPHENYL]-8,9-DIHYDRO-7H-BENZO[7]ANNULENE-2-CARBOXYLATE AND A SALT THEREOF SANOFI SA (FR) 2022-05-18 EP claimed
CN-113620795-A Method for synthesizing benzocycloheptenone compounds 河南师范大学 2021-11-09 CN claimed
CN-107298640-B Preparation method and application of methylene ketone compound 曲阜师范大学 2020-08-04 CN claimed
CN-106554265-A A kind of preparation method of 1- benzosuberones 四川同晟生物科技有限公司 2017-04-05 CN claimed
EP-3129767-A1 REACTIVE LABELLING COMPOUNDS AND USES THEREOF Academia Sinica (TW) 2017-02-15 EP claimed
CN-106415244-A Reactive marker compounds and uses thereof 中央研究院 2017-02-15 CN claimed
WO-2015148915-A9 REACTIVE LABELLING COMPOUNDS AND USES THEREOF ACADEMIA SINICA (TW) 2016-12-22 WO claimed
EP-0743574-A2 Migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
US-5563014-A SOFTENABLE LAYER CONTAINIG PHOTOSENSITIVE MARKING MATERIAL; TRANSPARENTIZING AGENT XEROX CORPORATION (US) 1996-10-08 US claimed
US-5514505-A SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE XEROX CORPORATION (US) 1996-05-07 US claimed
EP-0484820-B1 Silver halide photographic material FUJI PHOTO FILM CO LTD (JP) 1995-07-26 EP claimed
US-5272050-A Silver halide photographic material FUJI PHOTO FILM CO., LTD. (JP) 1993-12-21 US claimed
US-5227284-A emulsion layer or hydrophilic colloid layer contains light absorber which can be decolored without staining FUJI PHOTO FILM CO., LTD. (JP) 1993-07-13 US claimed
EP-0483809-A1 Silver halide photographic material FUJI PHOTO FILM CO., LTD. (JP) 1992-05-06 EP claimed
EP-0275524-B1 PROCESS FOR THE PREPARATION OF THIOPHENES FROM ALPHA-METHYL KETONES BY THE ONE-POT METHOD, AND ANELLATED THIOPHENES PREPARED BY MEANS OF THIS PROCESS Von der Haar-Czogalla, Rita (DE) 1991-05-15 EP claimed
US-4737442-A INCLUDING A SENSITIZER AND A BLOCKED DEVELOPMENT RESTRAINER; FREE OF BLACK SPOTS FUJI PHOTO FILM CO., LTD. (JP) 1988-04-12 US claimed
US-4435426-A ADRENERGIC BLOCKING AGENTS, FROM A HYDROXY-KETONE, EPICHLOROHYDRIN AND AN AMINE SOCIETE ANONYME DITE: SANOFI (FR) 1984-03-06 US claimed